UniProt P85421
Alpha-amanitin (P85421)
Alpha-amanitin (UniProt P85421): 22 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P85421
- Protein
- Alpha-amanitin
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 11 · 11 records with a druggable one
Structures
23 records of P85421 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1K83 | Crystal Structure of Yeast RNA Polymerase II Complexed with the Inhibitor Alpha Amanitin | x-ray diffraction | M | — | — |
| 1K83 | Crystal structure of yeast RNA polymerase II complexed with the inhibitor alpha amanitin | x-ray diffraction | M | — | — |
| 2VUM | Alpha-amanitin inhibited complete RNA polymerase II elongation complex | x-ray diffraction | M | — | — |
| 2VUM | Alpha-amanitin inhibited complete RNA polymerase II elongation complex | x-ray diffraction | M | — | — |
| 3CQZ | Crystal structure of 10 subunit RNA polymerase II in complex with the inhibitor alpha-amanitin | x-ray diffraction | M | — | — |
| 3CQZ | Crystal structure of 10 subunit RNA polymerase II in complex with the inhibitor alpha-amanitin | x-ray diffraction | M | — | — |
| 6EXV | Structure of mammalian RNA polymerase II elongation complex inhibited by Alpha-amanitin | electron microscopy | M | — | — |
| 8WAK | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II… | electron microscopy | N | — | — |
| 8WAL | Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II… | electron microscopy | N | — | 1 (best 0.82) |
| 8WAN | Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II… | electron microscopy | N | — | 1 (best 0.77) |
| 8WAO | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II… | electron microscopy | N | — | 1 (best 0.77) |
| 8WAQ | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II… | electron microscopy | N | — | 1 (best 0.82) |
| 8WAR | Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II… | electron microscopy | N | — | — |
| 8WAS | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II… | electron microscopy | N | — | — |
| 8WAT | De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt… | electron microscopy | N | — | 1 (best 0.79) |
| 8WAU | De novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt… | electron microscopy | N | — | 1 (best 0.78) |
| 8WAV | De novo transcribing complex 12 (TC12), the early elongation complex with Pol II positioned 12nt… | electron microscopy | N | — | — |
| 8WAW | De novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt… | electron microscopy | N | — | 1 (best 0.78) |
| 8WAX | De novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt… | electron microscopy | N | — | 1 (best 0.82) |
| 8WAY | De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt… | electron microscopy | N | — | 1 (best 0.78) |
| 8WAZ | De novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt… | electron microscopy | N | — | 1 (best 0.78) |
| 8WB0 | De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt… | electron microscopy | N | — | 1 (best 0.79) |
| P85421 | AlphaFold monomer V2.0 prediction for alpha-amanitin proprotein (P85421) | predicted | A | — | — |
Experiment against prediction
- 3CQZ chain M against the predicted model P85421: TM-score 0.34, RMSD 0.65 Å
- 3CQZ chain M against the predicted model P85421: TM-score 0.34, RMSD 0.65 Å
- 2VUM chain M against the predicted model P85421: TM-score 0.34, RMSD 0.68 Å
- 2VUM chain M against the predicted model P85421: TM-score 0.34, RMSD 0.68 Å
- 8WAV chain N against the predicted model P85421: TM-score 0.33, RMSD 0.63 Å
- 8WAU chain N against the predicted model P85421: TM-score 0.33, RMSD 0.63 Å
- 8WAN chain N against the predicted model P85421: TM-score 0.33, RMSD 0.63 Å
- 8WAW chain N against the predicted model P85421: TM-score 0.33, RMSD 0.63 Å
- 8WAZ chain N against the predicted model P85421: TM-score 0.33, RMSD 0.63 Å
- 8WAT chain N against the predicted model P85421: TM-score 0.33, RMSD 0.63 Å
Elsewhere
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