UniProt P85100
Myosin light chain 3 (P85100)
Myosin light chain 3 (UniProt P85100): 6 experimental structures and 1 predicted model on GenesisL1, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P85100
- Protein
- Myosin light chain 3
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 17 · 5 records with a druggable one
Structures
7 records of P85100 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5N69 | Cardiac muscle myosin S1 fragment in the pre-powerstroke state co-crystallized with the activator… | x-ray diffraction | G, H | — | 4 (best 0.64) |
| 5N69 | Cardiac muscle myosin S1 fragment in the pre-powerstroke state co- crystallized with the activator… | x-ray diffraction | G, H | — | — |
| 6FSA | Beta-Cardiac myosin post-rigor | x-ray diffraction | D, H | — | 4 (best 0.53) |
| 6FSA | Beta-cardiac myosin post-rigor | x-ray diffraction | D, H | — | — |
| 8QYQ | Beta-cardiac myosin S1 fragment in the pre-powerstroke state complexed to Mavacamten | x-ray diffraction | C, D | — | 3 (best 0.86) |
| 8QYU | Beta-cardiac myosin S1 fragment in the pre-powerstroke state complexed to Omecamtiv mecarbil | x-ray diffraction | G, H | — | 5 (best 0.85) |
| P85100 | AlphaFold monomer V2.0 prediction for myosin light chain 3 (P85100) | predicted | A | — | 1 (best 0.55) |
Experiment against prediction
- 8QYQ chain C against the predicted model P85100: TM-score 0.99, RMSD 0.57 Å
- 8QYU chain G against the predicted model P85100: TM-score 0.98, RMSD 0.59 Å
- 5N69 chain G against the predicted model P85100: TM-score 0.98, RMSD 0.87 Å
- 5N69 chain G against the predicted model P85100: TM-score 0.98, RMSD 0.87 Å
- 6FSA chain H against the predicted model P85100: TM-score 0.97, RMSD 0.79 Å
- 6FSA chain H against the predicted model P85100: TM-score 0.97, RMSD 0.79 Å
- 6FSA chain D against the predicted model P85100: TM-score 0.97, RMSD 0.81 Å
- 6FSA chain D against the predicted model P85100: TM-score 0.97, RMSD 0.81 Å
- 8QYU chain H against the predicted model P85100: TM-score 0.97, RMSD 0.83 Å
- 8QYQ chain D against the predicted model P85100: TM-score 0.97, RMSD 0.58 Å
Elsewhere
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