UniProt P84103

Serine/arginine-rich splicing factor 3 (P84103)

Serine/arginine-rich splicing factor 3 (UniProt P84103): 5 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P84103
Protein: Serine/arginine-rich splicing factor 3
Experimental structures: 5
Predicted models: 1
Pockets: 4 · 1 record with a druggable one

Structures

6 records of P84103 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
2I2Y	Solution structure of the RRM of SRp20 bound to the RNA CAUC	solution nmr	A	—	—
2I2Y	Solution structure of the rrm of SRP20 bound to the RNA cauc	solution nmr	A	—	—
2I38	Solution structure of the RRM of SRp20	solution nmr	A	—	—
2I38	Solution structure of the rrm of SRP20	solution nmr	A	—	—
9ASQ	Human Drosha, DGCR8 and SRSF3 in complex with Pri-let-7f1	electron microscopy	H	—	4 (best 0.85)
P84103	AlphaFold monomer V2.0 prediction for SERINE/ARGININE-rich splicing factor 3 (P84103)	predicted	A	—	—

Experiment against prediction

9ASQ chain H against the predicted model P84103: TM-score 0.87, RMSD 1.48 Å
2I2Y chain A against the predicted model P84103: TM-score 0.48, RMSD 2.58 Å
2I2Y chain A against the predicted model P84103: TM-score 0.48, RMSD 2.58 Å
2I38 chain A against the predicted model P84103: TM-score 0.47, RMSD 2.89 Å
2I38 chain A against the predicted model P84103: TM-score 0.47, RMSD 2.89 Å
2I2Y chain A against the predicted model P19909: TM-score 0.38, RMSD 3.54 Å
2I2Y chain A against the predicted model P19909: TM-score 0.38, RMSD 3.54 Å
2I38 chain A against the predicted model P19909: TM-score 0.38, RMSD 2.74 Å
2I38 chain A against the predicted model P19909: TM-score 0.38, RMSD 2.74 Å

Elsewhere

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