UniProt P84091
AP-2 complex subunit mu (P84091)
AP-2 complex subunit mu (UniProt P84091): 12 experimental structures and 1 predicted model on GenesisL1, 52 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P84091
- Protein
- AP-2 complex subunit mu
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 52 · 5 records with a druggable one
Structures
13 records of P84091 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6OWO | Cryo-EM structure of phosphorylated ap-2 core bound to necap | electron microscopy | M | — | 13 (best 0.83) |
| 6OWO | Cryo-EM structure of phosphorylated ap-2 core bound to necap | electron microscopy | M | — | — |
| 6OXL | CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 (mu E302K) BOUND TO NECAP IN THE PRESENCE OF SS DNA | electron microscopy | M | — | 12 (best 0.85) |
| 6OXL | Cryo-EM structure of phosphorylated ap-2 (mu E302K) bound to necap in the presence of ss DNA | electron microscopy | M | — | — |
| 7RW8 | AP2 bound to heparin in the closed conformation | electron microscopy | M | — | — |
| 7RW9 | AP2 bound to heparin in the bowl conformation | electron microscopy | M | — | — |
| 7RWA | AP2 bound to heparin and Tgn38 tyrosine cargo peptide | electron microscopy | M, m | — | 6 (best 0.81) |
| 7RWA | AP2 bound to heparin and TGN38 tyrosine cargo peptide | electron microscopy | M, m | — | — |
| 7RWB | AP2 bound to the APA domain of SGIP in the presence of heparin | electron microscopy | M, m | — | 10 (best 0.82) |
| 7RWB | AP2 bound to the apa domain of sgip in the presence of heparin | electron microscopy | M, m | — | — |
| 7RWC | AP2 bound to the apa domain of sgip and heparin; partial signal subtraction and symmetry expansion | electron microscopy | M | — | — |
| 8T1O | AP2 bound to MSP2N2 nanodisc with Tgn38 cargo peptide; composite map | electron microscopy | M | — | 11 (best 0.79) |
| P84091 | AlphaFold monomer V2.0 prediction for ap-2 complex subunit mu (P84091) | predicted | A | — | — |
Experiment against prediction
- 7RW9 chain M against the predicted model P84091: TM-score 0.96, RMSD 0.95 Å
- 7RWA chain m against the predicted model P84091: TM-score 0.94, RMSD 1.94 Å
- 7RWA chain m against the predicted model P84091: TM-score 0.94, RMSD 1.94 Å
- 7RWA chain M against the predicted model P84091: TM-score 0.94, RMSD 1.94 Å
- 7RWA chain M against the predicted model P84091: TM-score 0.94, RMSD 1.94 Å
- 8T1O chain M against the predicted model P84091: TM-score 0.93, RMSD 2.15 Å
- 6OXL chain M against the predicted model P84091: TM-score 0.61, RMSD 1.74 Å
- 6OXL chain M against the predicted model P84091: TM-score 0.61, RMSD 1.74 Å
- 7RW8 chain M against the predicted model P84091: TM-score 0.60, RMSD 1.84 Å
- 6OWO chain M against the predicted model P84091: TM-score 0.60, RMSD 1.64 Å
Elsewhere
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