UniProt P84051
Histone H2A (P84051)
Histone H2A (UniProt P84051): 19 experimental structures and 1 predicted model on GenesisL1, 61 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P84051
- Protein
- Histone H2A
- Experimental structures
- 19
- Predicted models
- 1
- Pockets
- 61 · 6 records with a druggable one
Structures
20 records of P84051 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2NQB | Drosophila Nucleosome Structure | x-ray diffraction | C, G | — | — |
| 2NQB | Drosophila nucleosome structure | x-ray diffraction | C, G | — | — |
| 2PYO | Drosophila nucleosome core | x-ray diffraction | C, G | — | — |
| 2PYO | Drosophila nucleosome core | x-ray diffraction | C, G | — | — |
| 4QLC | Crystal structure of chromatosome at 3.5 angstrom resolution | x-ray diffraction | C, G | — | — |
| 4QLC | Crystal structure of chromatosome at 3.5 ångström resolution | x-ray diffraction | C, G | — | — |
| 4X23 | Crystal structure of cenp-C in complex with the nucleosome core particle | x-ray diffraction | C, G, M, Q | — | — |
| 4X23 | Crystal structure of cenp-C in complex with the nucleosome core particle | x-ray diffraction | C, G, M, Q | — | — |
| 5WCU | Crystal structure of 167 bp nucleosome bound to the globular domain of linker histone H5 | x-ray diffraction | C, G, M, Q | — | 14 (best 0.82) |
| 5WCU | Crystal structure of 167 bp nucleosome bound to the globular domain of linker histone H5 | x-ray diffraction | C, G, M, Q | — | — |
| 6DZT | Cryo-EM structure of nucleosome in complex with a single chain antibody fragment | electron microscopy | C, G | — | — |
| 6PWE | Cryo-EM structure of nucleosome core particle | electron microscopy | C, G | — | 10 (best 0.79) |
| 6PWE | Cryo-EM structure of nucleosome core particle | electron microscopy | C, G | — | — |
| 6PWF | Cryo-EM structure of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome | electron microscopy | C, G | — | 8 (best 0.79) |
| 6PWF | Cryo-EM structure of the ATPase domain of chromatin remodeling factor iswi bound to the nucleosome | electron microscopy | C, G | — | — |
| 7PJ1 | Solution structure of isolated Drosophila histone H2A-H2B heterodimer | solution nmr | A | — | 2 (best 0.71) |
| 7PJ1 | Solution structure of isolated drosophila histone H2A-H2B heterodimer | solution nmr | A | — | — |
| 7XYG | Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+3 position of the nucleosome | electron microscopy | C, G | — | 14 (best 0.80) |
| 8PP6 | human RYBP-PRC1 bound to H2AK118ub1 nucleosome | electron microscopy | C, G | — | 13 (best 0.78) |
| P84051 | AlphaFold monomer V2.0 prediction for histone H2A (P84051) | predicted | A | — | — |
Experiment against prediction
- 4QLC chain C against the predicted model P84051: TM-score 0.97, RMSD 0.68 Å
- 4QLC chain C against the predicted model P84051: TM-score 0.97, RMSD 0.68 Å
- 5WCU chain Q against the predicted model P84051: TM-score 0.97, RMSD 0.72 Å
- 2NQB chain G against the predicted model P84051: TM-score 0.96, RMSD 0.74 Å
- 2NQB chain G against the predicted model P84051: TM-score 0.96, RMSD 0.74 Å
- 4X23 chain C against the predicted model P84051: TM-score 0.96, RMSD 0.74 Å
- 4X23 chain C against the predicted model P84051: TM-score 0.96, RMSD 0.74 Å
- 5WCU chain G against the predicted model P84051: TM-score 0.96, RMSD 0.75 Å
- 5WCU chain G against the predicted model P84051: TM-score 0.96, RMSD 0.75 Å
- 5WCU chain C against the predicted model P84051: TM-score 0.96, RMSD 0.81 Å
Elsewhere
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