UniProt P78552
Interleukin-13 receptor alpha-1 chain (P78552)
Interleukin-13 receptor alpha-1 chain (UniProt P78552): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 46 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P78552
- Protein
- Interleukin-13 receptor alpha-1 chain
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 46 · 8 records with a druggable one
Structures
9 records of P78552 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3BPN | Crystal structure of the IL4-IL4R-IL13Ra ternary complex | x-ray diffraction | C | — | 6 (best 0.66) |
| 3BPN | Crystal structure of the IL4-IL4R-IL13RA ternary complex | x-ray diffraction | C | — | 6 (best 0.66) |
| 3BPO | Crystal structure of the IL13-IL4R-IL13Ra ternary complex | x-ray diffraction | C | — | 7 (best 0.61) |
| 3BPO | Crystal structure of the IL13-IL4R-IL13RA ternary complex | x-ray diffraction | C | — | 7 (best 0.61) |
| 4HWB | Crystal structure of ectodomain 3 of the IL-13 receptor alpha 1 in complex with a human… | x-ray diffraction | A | SO4 | 4 (best 0.55) |
| 4HWB | Crystal structure of ectodomain 3 of the il-13 receptor alpha 1 in complex with a human… | x-ray diffraction | A | SO4 | 4 (best 0.55) |
| 5E4E | Engineered Interleukin-13 bound to receptor | x-ray diffraction | C | SO4, NAG | 6 (best 0.63) |
| 5E4E | Engineered interleukin-13 bound to receptor | x-ray diffraction | C | SO4, NAG | 6 (best 0.63) |
| P78552 | AlphaFold monomer V2.0 prediction for interleukin-13 receptor subunit alpha-1 (P78552) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5E4E chain C against the predicted model P78552: TM-score 0.99, RMSD 0.75 Å
- 5E4E chain C against the predicted model P78552: TM-score 0.99, RMSD 0.75 Å
- 3BPO chain C against the predicted model P78552: TM-score 0.98, RMSD 0.88 Å
- 3BPO chain C against the predicted model P78552: TM-score 0.98, RMSD 0.88 Å
- 3BPN chain C against the predicted model P78552: TM-score 0.98, RMSD 0.91 Å
- 3BPN chain C against the predicted model P78552: TM-score 0.98, RMSD 0.91 Å
- 4HWB chain A against the predicted model P78552: TM-score 0.46, RMSD 3.03 Å
- 4HWB chain A against the predicted model P78552: TM-score 0.46, RMSD 3.03 Å
Elsewhere
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