UniProt P78504
Protein jagged-1 (P78504)
Protein jagged-1 (UniProt P78504): 12 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P78504
- Protein
- Protein jagged-1
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
13 records of P78504 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2KB9 | Human Jagged-1, exon 6 | solution nmr | A | — | — |
| 2KB9 | Human jagged-1, exon 6 | solution nmr | A | — | — |
| 2VJ2 | Human Jagged-1, domains DSL and EGFs1-3 | x-ray diffraction | A, B | — | — |
| 2VJ2 | Human jagged-1, domains dsl and EGFS1-3 | x-ray diffraction | A, B | — | — |
| 4CBZ | Notch ligand, Jagged-1, contains an N-terminal C2 domain | x-ray diffraction | A, B | — | — |
| 4CBZ | Notch ligand, jagged-1, contains an N-terminal C2 domain | x-ray diffraction | A, B | — | — |
| 4CC0 | Notch ligand, Jagged-1, contains an N-terminal C2 domain | x-ray diffraction | A, B | — | — |
| 4CC0 | Notch ligand, jagged-1, contains an N-terminal C2 domain | x-ray diffraction | A, B | — | — |
| 4CC1 | Notch ligand, Jagged-1, contains an N-terminal C2 domain | x-ray diffraction | A, B | — | — |
| 4CC1 | Notch ligand, jagged-1, contains an N-terminal C2 domain | x-ray diffraction | A, B | — | — |
| 5BO1 | Crystal structure of a human Jag1 fragment in complex with an anti-Jag1 Fab | x-ray diffraction | A, B | — | 2 (best 0.54) |
| 5BO1 | Crystal structure of a human JAG1 fragment in complex with an anti- JAG1 Fab | x-ray diffraction | A, B | — | — |
| P78504 | AlphaFold monomer V2.0 prediction for protein jagged-1 (P78504) | predicted | A | — | — |
Experiment against prediction
- 4CBZ chain B against the predicted model P78504: TM-score 0.99, RMSD 0.59 Å
- 4CBZ chain B against the predicted model P78504: TM-score 0.99, RMSD 0.59 Å
- 4CC0 chain B against the predicted model P78504: TM-score 0.98, RMSD 0.78 Å
- 4CC0 chain B against the predicted model P78504: TM-score 0.98, RMSD 0.78 Å
- 4CC1 chain A against the predicted model P78504: TM-score 0.96, RMSD 1.31 Å
- 4CC1 chain A against the predicted model P78504: TM-score 0.96, RMSD 1.31 Å
- 4CC0 chain A against the predicted model P78504: TM-score 0.96, RMSD 1.33 Å
- 4CC0 chain A against the predicted model P78504: TM-score 0.96, RMSD 1.33 Å
- 4CBZ chain A against the predicted model P78504: TM-score 0.94, RMSD 1.76 Å
- 4CBZ chain A against the predicted model P78504: TM-score 0.94, RMSD 1.76 Å
Elsewhere
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