UniProt P78358
Cancer/testis antigen 1 (P78358)
Cancer/testis antigen 1 (UniProt P78358): 18 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P78358
- Protein
- Cancer/testis antigen 1
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 11 · 3 records with a druggable one
Structures
19 records of P78358 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2F53 | Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances… | x-ray diffraction | C | — | — |
| 2F53 | Directed evolution of human T-cell receptor CDR2 residues by phage display dramatically enhances… | x-ray diffraction | C | — | — |
| 2F54 | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances… | x-ray diffraction | C, H | — | — |
| 2F54 | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances… | x-ray diffraction | C, H | — | — |
| 2P5E | Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC Reveal Native Diagonal… | x-ray diffraction | C | — | — |
| 2P5E | Crystal structures of high affinity human T-cell receptors bound to pmhc reveal native diagonal… | x-ray diffraction | C | — | — |
| 2P5W | Crystal structures of high affinity human T-cell receptors bound to pMHC reveal native diagonal… | x-ray diffraction | C | — | — |
| 2P5W | Crystal structures of high affinity human T-cell receptors bound to pmhc reveal native diagonal… | x-ray diffraction | C | — | — |
| 2PYE | Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC RevealNative Diagonal… | x-ray diffraction | C | — | — |
| 2PYE | Crystal structures of high affinity human T-cell receptors bound to pmhc revealnative diagonal… | x-ray diffraction | C | — | — |
| 3KLA | Ca2+ release from the endoplasmic reticulum of NY-ESO-1 specific T cells is modulated by the… | x-ray diffraction | C, F | — | — |
| 3KLA | CA2+ release from the endoplasmic reticulum of ny-eso-1 specific T cells is modulated by the… | x-ray diffraction | C, F | — | — |
| 6AT5 | Crystal structure of HLA-B*07:02 in complex with an NY-ESO-1 peptide | x-ray diffraction | C | — | 1 (best 0.46) |
| 6AT5 | Crystal structure of HLA-B*07:02 in complex with an ny-eso-1 peptide | x-ray diffraction | C | — | — |
| 6RP9 | Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV | x-ray diffraction | C, H | — | 2 (best 0.60) |
| 6RP9 | Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01- sllmwitqv | x-ray diffraction | C, H | — | — |
| 9C3E | TCR - CD3 complex bound to HLA | electron microscopy | H | — | 7 (best 0.65) |
| 9DL1 | Crystal Structure of HLA-A*02:01/NY-ESO-1 (SLLMWITQV) and a target specific TRACeR-I | x-ray diffraction | E, H | — | 1 (best 0.75) |
| P78358 | AlphaFold monomer V2.0 prediction for CANCER/TESTIS antigen 1 (P78358) | predicted | A | — | — |
Experiment against prediction
- 9C3E chain H against the predicted model P61769: TM-score 0.25, RMSD 1.50 Å
- 2F53 chain C against the predicted model P78358: TM-score 0.41, RMSD 0.54 Å
- 2F53 chain C against the predicted model P78358: TM-score 0.41, RMSD 0.54 Å
- 2F54 chain H against the predicted model P78358: TM-score 0.36, RMSD 0.91 Å
- 2F54 chain H against the predicted model P78358: TM-score 0.36, RMSD 0.91 Å
- 3KLA chain F against the predicted model P78358: TM-score 0.34, RMSD 1.69 Å
- 3KLA chain F against the predicted model P78358: TM-score 0.34, RMSD 1.69 Å
- 3KLA chain C against the predicted model P78358: TM-score 0.33, RMSD 1.69 Å
- 3KLA chain C against the predicted model P78358: TM-score 0.33, RMSD 1.69 Å
- 2F54 chain C against the predicted model P78358: TM-score 0.33, RMSD 0.91 Å
Elsewhere
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