UniProt P70604
Small conductance calcium-activated potassium channel protein 2 (P70604)
Small conductance calcium-activated potassium channel protein 2 (UniProt P70604): 22 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against…
- UniProt
- P70604
- Protein
- Small conductance calcium-activated potassium channel protein 2
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
23 records of P70604 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1G4Y | 1.60 a crystal structure of the gating domain from small conductance potassium channel complexed… | x-ray diffraction | B | — | — |
| 1G4Y | 1.60 a crystal structure of the gating domain from small conductance potassium channel complexed… | x-ray diffraction | B | — | — |
| 1KKD | Solution structure of the calmodulin binding domain (CaMBD) of small conductance Ca2+-activated… | solution nmr | A | — | — |
| 1KKD | Solution structure of the calmodulin binding domain (cambd) of small conductance CA2+-activated… | solution nmr | A | — | — |
| 1QX7 | Crystal structure of apoCaM bound to the gating domain of small conductance Ca2+-activated… | x-ray diffraction | D | — | — |
| 1QX7 | Crystal structure of apocam bound to the gating domain of small conductance CA2+-activated… | x-ray diffraction | D | — | — |
| 2PNV | Crystal Structure of the leucine zipper domain of small-conductance Ca2+-activated K+ (SKCa)… | x-ray diffraction | A, B | — | — |
| 2PNV | Crystal structure of the leucine zipper domain of small- conductance CA2+-activated K+ (skca)… | x-ray diffraction | A, B | — | — |
| 3SJQ | Crystal structure of a small conductance potassium channel splice variant complexed with… | x-ray diffraction | C, D | — | — |
| 3SJQ | Crystal structure of a small conductance potassium channel splice variant complexed with… | x-ray diffraction | C, D | — | — |
| 4G27 | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium… | x-ray diffraction | B | — | — |
| 4G27 | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium… | x-ray diffraction | B | — | — |
| 4G28 | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium… | x-ray diffraction | B | — | — |
| 4G28 | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium… | x-ray diffraction | B | — | — |
| 4J9Y | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium… | x-ray diffraction | B | — | — |
| 4J9Y | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium… | x-ray diffraction | B | — | — |
| 4J9Z | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium… | x-ray diffraction | B | — | — |
| 4J9Z | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium… | x-ray diffraction | B | — | — |
| 4QNH | Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance… | x-ray diffraction | B | — | — |
| 4QNH | Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance… | x-ray diffraction | B | — | — |
| 6CZQ | A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C.… | x-ray diffraction | B | SO4 | 2 (best 0.37) |
| 6CZQ | A V-to-F substitution in SK2 channels causes CA2+ hypersensitivity and improves locomotion in a C.… | x-ray diffraction | B | SO4 | — |
| P70604 | AlphaFold monomer V2.0 prediction for small conductance calcium- activated potassium channel… | predicted | A | — | 5 (best 0.60) |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 2PNV chain A against the predicted model P70604: TM-score 0.88, RMSD 0.73 Å
- 2PNV chain A against the predicted model P70604: TM-score 0.88, RMSD 0.73 Å
- 1QX7 chain D against the predicted model P70604: TM-score 0.85, RMSD 0.24 Å
- 1QX7 chain D against the predicted model P70604: TM-score 0.85, RMSD 0.24 Å
- 3SJQ chain D against the predicted model P70604: TM-score 0.81, RMSD 1.48 Å
- 3SJQ chain D against the predicted model P70604: TM-score 0.81, RMSD 1.48 Å
- 3SJQ chain C against the predicted model P70604: TM-score 0.81, RMSD 1.47 Å
- 3SJQ chain C against the predicted model P70604: TM-score 0.81, RMSD 1.47 Å
- 1G4Y chain B against the predicted model P70604: TM-score 0.75, RMSD 2.08 Å
- 1G4Y chain B against the predicted model P70604: TM-score 0.75, RMSD 2.08 Å
Elsewhere
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