UniProt P69801

PTS system mannose-specific EIIC component (P69801)

PTS system mannose-specific EIIC component (UniProt P69801): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 37 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…

UniProt: P69801
Protein: PTS system mannose-specific EIIC component
Experimental structures: 4
Predicted models: 1
Ligands: 1
Pockets: 37 · 3 records with a druggable one

Structures

5 records of P69801 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6K1H	Structure of membrane protein	electron microscopy	Y, E, B	MAN	16 (best 0.88)
6K1H	Structure of membrane protein	electron microscopy	Y, E, B	MAN	—
7DYR	CryoEM Structure of Mannose Transporter ManYZ and Microcin E492 (MceA) complex	electron microscopy	Y, B, E	MAN	18 (best 0.88)
7DYR	Cryoem structure of mannose transporter manyz and microcin E492 (mcea) complex	electron microscopy	Y, B, E	MAN	—
P69801	AlphaFold monomer V2.0 prediction for pts system mannose-specific eiic component (P69801)	predicted	A	—	3 (best 0.56)

Ligands

MAN · alpha-D-mannopyranose · in 4 records

Experiment against prediction

6K1H chain B against the predicted model P69801: TM-score 0.76, RMSD 3.17 Å
6K1H chain E against the predicted model P69801: TM-score 0.76, RMSD 3.17 Å
6K1H chain Y against the predicted model P69801: TM-score 0.76, RMSD 3.16 Å
6K1H chain Y against the predicted model P69801: TM-score 0.76, RMSD 3.16 Å
7DYR chain Y against the predicted model P69801: TM-score 0.66, RMSD 1.71 Å
7DYR chain Y against the predicted model P69801: TM-score 0.66, RMSD 1.71 Å
7DYR chain E against the predicted model P69801: TM-score 0.66, RMSD 1.71 Å
7DYR chain B against the predicted model P69801: TM-score 0.66, RMSD 1.71 Å

Elsewhere

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