UniProt P68137
Actin, alpha skeletal muscle (P68137)
Actin, alpha skeletal muscle (UniProt P68137): 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P68137
- Protein
- Actin, alpha skeletal muscle
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
3 records of P68137 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NOJ | Ca2+-induced Movement of Tropomyosin on Native Cardiac Thin Filaments - "OPEN" state | electron microscopy | A, B, C, D, E | ADP, MG | 20 (best 0.81) |
| 5NOJ | CA2+-induced movement of tropomyosin on native cardiac thin filaments - "open" state | electron microscopy | A, B, C, D, E | ADP, MG | — |
| P68137 | AlphaFold monomer V2.0 prediction for actin, alpha skeletal muscle (P68137) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5NOJ chain D against the predicted model P68137: TM-score 0.96, RMSD 1.58 Å
- 5NOJ chain D against the predicted model P68137: TM-score 0.96, RMSD 1.58 Å
- 5NOJ chain E against the predicted model P68137: TM-score 0.96, RMSD 1.58 Å
- 5NOJ chain E against the predicted model P68137: TM-score 0.96, RMSD 1.58 Å
- 5NOJ chain C against the predicted model P68137: TM-score 0.96, RMSD 1.58 Å
- 5NOJ chain C against the predicted model P68137: TM-score 0.96, RMSD 1.58 Å
- 5NOJ chain B against the predicted model P68137: TM-score 0.96, RMSD 1.58 Å
- 5NOJ chain B against the predicted model P68137: TM-score 0.96, RMSD 1.58 Å
- 5NOJ chain A against the predicted model P68137: TM-score 0.96, RMSD 1.58 Å
- 5NOJ chain A against the predicted model P68137: TM-score 0.96, RMSD 1.58 Å
Elsewhere
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