UniProt P68134
Actin, alpha skeletal muscle (P68134)
Actin, alpha skeletal muscle (UniProt P68134): 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P68134
- Protein
- Actin, alpha skeletal muscle
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 30 · 2 records with a druggable one
Structures
11 records of P68134 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4B1U | Structure of the Phactr1 RPEL domain and RPEL motif directed assemblies with G-actin reveal the… | x-ray diffraction | B | — | — |
| 4B1U | Structure of the PHACTR1 rpel domain and rpel motif directed assemblies with G-actin reveal the… | x-ray diffraction | B | — | — |
| 6KLL | F-actin of cardiac thin filament in low-calcium state | electron microscopy | A, B, C, D | MG, ADP | — |
| 6KLL | F-actin of cardiac thin filament in low-calcium state | electron microscopy | A, B, C, D | MG, ADP | — |
| 6KLN | F-actin of cardiac thin filament in high-calcium state | electron microscopy | A, B, C, D | MG, ADP | — |
| 6KLN | F-actin of cardiac thin filament in high-calcium state | electron microscopy | A, B, C, D | MG, ADP | — |
| 7NEP | Homology model of the in situ actomyosin complex from the A-band of mouse psoas muscle sarcomere in… | electron microscopy | A, B, C, D, E, F, G, H, I, J, K | — | 18 (best 0.84) |
| 7NEP | Homology model of the in situ actomyosin complex from the a-band of mouse psoas muscle sarcomere in… | electron microscopy | A, B, C, D, E, F, G, H, I, J, K | — | — |
| 7QIN | In situ structure of actomyosin complex in skeletal sarcomere | electron microscopy | A, B, C, D, E | ADP, MG | 12 (best 0.87) |
| 7QIN | In situ structure of actomyosin complex in skeletal sarcomere | electron microscopy | A, B, C, D, E | ADP, MG | — |
| P68134 | AlphaFold monomer V2.0 prediction for actin, alpha skeletal muscle (P68134) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4B1U chain B against the predicted model P68134: TM-score 0.99, RMSD 0.77 Å
- 4B1U chain B against the predicted model P68134: TM-score 0.99, RMSD 0.77 Å
- 7NEP chain F against the predicted model P68134: TM-score 0.96, RMSD 1.53 Å
- 7NEP chain F against the predicted model P68134: TM-score 0.96, RMSD 1.53 Å
- 7NEP chain K against the predicted model P68134: TM-score 0.96, RMSD 1.53 Å
- 7NEP chain K against the predicted model P68134: TM-score 0.96, RMSD 1.53 Å
- 7NEP chain C against the predicted model P68134: TM-score 0.96, RMSD 1.53 Å
- 7NEP chain D against the predicted model P68134: TM-score 0.96, RMSD 1.53 Å
- 7NEP chain G against the predicted model P68134: TM-score 0.96, RMSD 1.53 Å
- 7NEP chain C against the predicted model P68134: TM-score 0.96, RMSD 1.53 Å
Elsewhere
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