UniProt P67589
Tryptophan--tRNA ligase (P67589)
Tryptophan--tRNA ligase (UniProt P67589), EC 6.1.1.2: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P67589
- Protein
- Tryptophan--tRNA ligase
- EC
- 6.1.1.2
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 16 · 3 records with a druggable one
Structures
3 records of P67589 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5V0I | Crystal Structure of Tryptophanyl-tRNA Synthetase from Escherichia coli Complexed with AMP and… | x-ray diffraction | A, B | AMP, TRP | 7 (best 0.74) |
| 5V0I | Crystal structure of tryptophanyl-tRNA synthetase from escherichia COLI complexed with AMP and… | x-ray diffraction | A, B | AMP, TRP | 7 (best 0.74) |
| P67589 | AlphaFold monomer V2.0 prediction for tryptophan--tRNA ligase (P67589) | predicted | A | — | 2 (best 0.72) |
Ligands
Experiment against prediction
- 5V0I chain A against the predicted model P67589: TM-score 0.98, RMSD 1.09 Å
- 5V0I chain A against the predicted model P67589: TM-score 0.98, RMSD 1.09 Å
- 5V0I chain B against the predicted model P67589: TM-score 0.97, RMSD 1.37 Å
- 5V0I chain B against the predicted model P67589: TM-score 0.97, RMSD 1.37 Å
Elsewhere
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