UniProt P63328
Protein phosphatase 3 catalytic subunit alpha (P63328)
Protein phosphatase 3 catalytic subunit alpha (UniProt P63328), EC 3.1.3.16: 5 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 32 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P63328
- Protein
- Protein phosphatase 3 catalytic subunit alpha
- EC
- 3.1.3.16
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 32 · 6 records with a druggable one
Structures
6 records of P63328 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4ORB | Crystal structure of mouse calcineurin | x-ray diffraction | A | ZN, FE | 4 (best 0.64) |
| 4ORB | Crystal structure of mouse calcineurin | x-ray diffraction | A | ZN, FE | 4 (best 0.64) |
| 9CHU | Cryo-EM structure of calcineurin fused beta2 adrenergic receptor in norepinephrine bound inactive… | electron microscopy | B | FK5 | 5 (best 0.79) |
| 9CHV | cryo-EM structure of calcineurin-fused beta2 adrenergic receptor in apo state | electron microscopy | B | FK5 | 7 (best 0.82) |
| 9CHX | cryo-EM structure of calcineurin-fused beta2 adrenergic receptor in carazolol bound inactive state | electron microscopy | B | FK5 | 8 (best 0.80) |
| P63328 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase 2B catalytic subunit… | predicted | A | — | 4 (best 0.70) |
Ligands
Experiment against prediction
- 4ORB chain A against the predicted model P63328: TM-score 0.99, RMSD 0.58 Å
- 4ORB chain A against the predicted model P63328: TM-score 0.99, RMSD 0.58 Å
- 9CHU chain B against the predicted model P63328: TM-score 0.98, RMSD 0.98 Å
- 9CHX chain B against the predicted model P63328: TM-score 0.98, RMSD 1.06 Å
- 9CHV chain B against the predicted model P63328: TM-score 0.96, RMSD 1.41 Å
Elsewhere
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