UniProt P63267
Actin, gamma-enteric smooth muscle (P63267)
Actin, gamma-enteric smooth muscle (UniProt P63267), EC 3.6.4.-: 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P63267
- Protein
- Actin, gamma-enteric smooth muscle
- EC
- 3.6.4.-
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
4 records of P63267 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6JAT | Crystal structure of SETD3 bound to Actin peptide and SFG | x-ray diffraction | B, D | — | — |
| 6JAT | Crystal structure of SETD3 bound to actin peptide and sfg | x-ray diffraction | B, D | — | — |
| 8V2Z | Cryo-EM Structure of Smooth Muscle Gamma Actin (ACTG2) Mutant R257C | electron microscopy | A, B, C, D, E | ADP, MG | 20 (best 0.81) |
| P63267 | AlphaFold monomer V2.0 prediction for actin, gamma-enteric smooth muscle (P63267) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8V2Z chain E against the predicted model P63267: TM-score 0.96, RMSD 1.47 Å
- 8V2Z chain C against the predicted model P63267: TM-score 0.96, RMSD 1.47 Å
- 8V2Z chain D against the predicted model P63267: TM-score 0.96, RMSD 1.47 Å
- 8V2Z chain A against the predicted model P63267: TM-score 0.96, RMSD 1.47 Å
- 8V2Z chain B against the predicted model P63267: TM-score 0.96, RMSD 1.48 Å
- 6JAT chain D against the predicted model P63267: TM-score 0.25, RMSD 1.97 Å
- 6JAT chain D against the predicted model P63267: TM-score 0.25, RMSD 1.97 Å
- 6JAT chain B against the predicted model P63267: TM-score 0.23, RMSD 0.58 Å
- 6JAT chain B against the predicted model P63267: TM-score 0.23, RMSD 0.58 Å
Elsewhere
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