UniProt P63241
Eukaryotic translation initiation factor 5A-1 (P63241)
Eukaryotic translation initiation factor 5A-1 (UniProt P63241): 5 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P63241
- Protein
- Eukaryotic translation initiation factor 5A-1
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
6 records of P63241 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3CPF | Crystal structure of human eukaryotic translation initiation factor EIF5A | x-ray diffraction | A, B | — | — |
| 3CPF | Crystal structure of human eukaryotic translation initiation factor EIF5A | x-ray diffraction | A, B | — | — |
| 5DLQ | Crystal structure of RanGTP-Exportin 4-eIF5A complex | x-ray diffraction | F, E | — | 8 (best 0.85) |
| 5DLQ | Crystal structure of rangtp-exportin 4-EIF5A complex | x-ray diffraction | F, E | — | — |
| 8Y0W | dormant ribosome with eIF5A, eEF2 and SERBP1 | electron microscopy | 5 | — | 1 (best 0.86) |
| P63241 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 5A-1 (P63241) | predicted | A | — | — |
Experiment against prediction
- 3CPF chain B against the predicted model P63241: TM-score 0.95, RMSD 0.93 Å
- 3CPF chain B against the predicted model P63241: TM-score 0.95, RMSD 0.93 Å
- 5DLQ chain E against the predicted model P63241: TM-score 0.95, RMSD 1.01 Å
- 5DLQ chain E against the predicted model P63241: TM-score 0.95, RMSD 1.01 Å
- 3CPF chain A against the predicted model P63241: TM-score 0.94, RMSD 1.07 Å
- 3CPF chain A against the predicted model P63241: TM-score 0.94, RMSD 1.07 Å
- 5DLQ chain F against the predicted model P63241: TM-score 0.93, RMSD 1.28 Å
- 5DLQ chain F against the predicted model P63241: TM-score 0.93, RMSD 1.28 Å
- 8Y0W chain 5 against the predicted model P63241: TM-score 0.89, RMSD 1.90 Å
Elsewhere
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