UniProt P63172
Dynein light chain Tctex-type 1 (P63172)
Dynein light chain Tctex-type 1 (UniProt P63172): 4 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P63172
- Protein
- Dynein light chain Tctex-type 1
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
5 records of P63172 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5JPW | Molecular basis for protein recognition specificity of the DYNLT1/Tctex1 canonical binding groove.… | solution nmr | A, B | — | — |
| 5JPW | Molecular basis for protein recognition specificity of the DYNLT1/TCTEX1 canonical binding groove.… | solution nmr | A, B | — | — |
| 8PR0 | Cytoplasmic dynein-A heavy chain bound to dynactin-p150glued and IC-LC tower | electron microscopy | G, H | — | 3 (best 0.81) |
| 8RGI | Structure of DYNLT1:DYNLT2B (TCTEX1:TCTEX1D2) heterodimer. | x-ray diffraction | A | — | 1 (best 0.41) |
| P63172 | AlphaFold monomer V2.0 prediction for dynein light chain tctex-type 1 (P63172) | predicted | A | — | — |
Experiment against prediction
- 8PR0 chain G against the predicted model P63172: TM-score 0.98, RMSD 0.56 Å
- 8RGI chain A against the predicted model P63172: TM-score 0.98, RMSD 0.56 Å
- 8PR0 chain H against the predicted model P63172: TM-score 0.98, RMSD 0.60 Å
- 5JPW chain B against the predicted model P63172: TM-score 0.50, RMSD 3.65 Å
- 5JPW chain B against the predicted model P63172: TM-score 0.50, RMSD 3.65 Å
- 5JPW chain A against the predicted model P63172: TM-score 0.50, RMSD 3.66 Å
- 5JPW chain A against the predicted model P63172: TM-score 0.50, RMSD 3.66 Å
- 5JPW chain A against the predicted model Q13409: TM-score 0.31, RMSD 5.21 Å
- 5JPW chain A against the predicted model Q13409: TM-score 0.31, RMSD 5.21 Å
- 5JPW chain B against the predicted model Q13409: TM-score 0.30, RMSD 5.27 Å
Elsewhere
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