UniProt P63097
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(i) subunit alpha-1 chimera (P63097)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(i) subunit alpha-1 chimera (UniProt P63097): 5 experimental structures and 1 predicted model on GenesisL1, 29 pockets. Binding…
- UniProt
- P63097
- Protein
- Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine…
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 29 · 4 records with a druggable one
Structures
6 records of P63097 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6K42 | cryo-EM structure of alpha2BAR-Gi1 complex | electron microscopy | A | — | 8 (best 0.83) |
| 6K42 | Cryo-EM structure of ALPHA2BAR-GI1 complex | electron microscopy | A | — | — |
| 8YH3 | A3R-Gi complex bound to m6A | electron microscopy | A, G | — | 8 (best 0.82) |
| 8YH6 | A3R-Gi complex bound to namodenoson | electron microscopy | G, A | — | 8 (best 0.82) |
| 9J5V | Human Lysophosphatidic Acid Receptor 1-Gi complex bound to CpY | electron microscopy | A | — | 5 (best 0.83) |
| P63097 | AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit alpha-1… | predicted | A | — | — |
Experiment against prediction
- 8YH3 chain G against the predicted model P59768: TM-score 0.90, RMSD 0.93 Å
- 8YH6 chain G against the predicted model P59768: TM-score 0.88, RMSD 1.06 Å
- 9J5V chain A against the predicted model P63097: TM-score 0.84, RMSD 2.77 Å
- 8YH3 chain A against the predicted model P63097: TM-score 0.81, RMSD 2.94 Å
- 8YH6 chain A against the predicted model P63097: TM-score 0.81, RMSD 3.01 Å
- 6K42 chain A against the predicted model P63097: TM-score 0.78, RMSD 3.30 Å
- 6K42 chain A against the predicted model P63097: TM-score 0.78, RMSD 3.30 Å
- 8YH6 chain A against the predicted model P59768: TM-score 0.16, RMSD 2.45 Å
- 8YH3 chain A against the predicted model P59768: TM-score 0.16, RMSD 2.44 Å
- 8YH3 chain G against the predicted model P63097: TM-score 0.42, RMSD 3.31 Å
Elsewhere
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