UniProt P62945
60S ribosomal protein L41 (P62945)
60S ribosomal protein L41 (UniProt P62945): 49 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62945
- Protein
- 60S ribosomal protein L41
- Experimental structures
- 49
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 14 · 13 records with a druggable one
Structures
50 records of P62945 in the MolNFT archive: 49 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UG0 | Structure of the human 80S ribosome | electron microscopy | Ln | — | — |
| 4V6X | Structure of the human 80S ribosome | electron microscopy | Cn | — | — |
| 5A2Q | Structure of the HCV IRES bound to the human ribosome | electron microscopy | h | — | 1 (best 0.86) |
| 5A2Q | Structure of the HCV ires bound to the human ribosome | electron microscopy | h | — | — |
| 5LKS | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | electron microscopy | Ln | — | — |
| 6G5H | Cryo-EM structure of a late human pre-40S ribosomal subunit - mature | electron microscopy | h | — | — |
| 6IP8 | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | electron microscopy | 2h | — | — |
| 6OLE | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs | electron microscopy | o | MG | — |
| 6OLF | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs | electron microscopy | o | MG | — |
| 6OLI | Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule… | electron microscopy | o | MG | — |
| 6OM7 | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and… | electron microscopy | o | MG | — |
| 6XA1 | Structure of a drug-like compound stalled human translation termination complex | electron microscopy | Ln | — | — |
| 6Y6X | Tetracenomycin X bound to the human ribosome | electron microscopy | Ln | — | 1 (best 0.85) |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | 9 | — | 1 (best 0.79) |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | 9 | — | — |
| 6Z6L | Cryo-EM structure of human CCDC124 bound to 80S ribosomes | electron microscopy | Ln | — | — |
| 6ZLW | SARS-cov-2 NSP1 bound to the human 40S ribosomal subunit | electron microscopy | h | — | — |
| 6ZMO | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | electron microscopy | Ln | — | 1 (best 0.86) |
| 6ZOJ | SARS-CoV-2-Nsp1-40S complex, composite map | electron microscopy | h | — | — |
| 6ZOJ | SARS-cov-2-NSP1-40S complex, composite MAP | electron microscopy | h | — | — |
| 6ZOK | SARS-cov-2-NSP1-40S complex, focused on body | electron microscopy | h | — | — |
| 7A09 | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | electron microscopy | W | — | — |
| 7K5I | SARS-cov-2 NSP1 in complex with human 40S ribosome | electron microscopy | h | — | — |
| 7QP6 | Structure of the human 48S initiation complex in open state (h48S AUG open) | electron microscopy | 9 | — | — |
| 7QP7 | Structure of the human 48S initiation complex in closed state (h48S AUG closed) | electron microscopy | 9 | — | — |
| 7QVP | Human collided disome (di-ribosome) stalled on XBP1 mRNA | electron microscopy | Ln, Mn | — | — |
| 7XNX | High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells | electron microscopy | Ln | — | — |
| 7XNY | High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells | electron microscopy | Ln | — | 1 (best 0.86) |
| 8G5Y | mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) | electron microscopy | Ln | — | — |
| 8G5Z | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) | electron microscopy | Ln | — | 1 (best 0.88) |
| 8G60 | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | electron microscopy | Ln | — | — |
| 8G61 | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | electron microscopy | Ln | MG | — |
| 8GLP | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU… | electron microscopy | Ln | — | 1 (best 0.87) |
| 8JDJ | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | electron microscopy | s | — | 1 (best 0.86) |
| 8JDK | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | electron microscopy | s | — | 2 (best 0.86) |
| 8K2C | Cryo-EM structure of the human 80S ribosome with Tigecycline | electron microscopy | Ln | MG | — |
| 8PJ1 | Structure of human 48S translation initiation complex in open codon scanning state (48S-1) | electron microscopy | 9 | — | — |
| 8PJ6 | Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3… | electron microscopy | 9 | — | 1 (best 0.85) |
| 8PPK | Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit | electron microscopy | h | — | — |
| 8PPL | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | electron microscopy | Ah | — | — |
| 8UKB | In situ HHT and CHX treated human hibernating state without E-tRNA 80S ribosome | electron microscopy | Ln | MG | — |
| 8XP3 | Cryo-EM structure of the human 40S ribosome with LARP1 and LRRC47 | electron microscopy | Ln | — | — |
| 8XSX | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | electron microscopy | Ln | — | 1 (best 0.86) |
| 8XXM | Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | electron microscopy | Ln | — | — |
| 8Y0W | dormant ribosome with eIF5A, eEF2 and SERBP1 | electron microscopy | Ln | — | 1 (best 0.86) |
| 8YOP | Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline | electron microscopy | Ln | — | — |
| 9C3H | Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site. | electron microscopy | So | — | — |
| 9G8M | human 80S ribosome bound by a SKI2-exosome complex | electron microscopy | Ln | — | — |
| 9G8O | human 40S ribosome bound by a SKI238-exosome complex | electron microscopy | Ln | — | 1 (best 0.84) |
| P62945 | AlphaFold monomer V2.0 prediction for 60S ribosomal protein L41 (P62945) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 7 records
Experiment against prediction
- 9C3H chain So against the predicted model P62945: TM-score 0.89, RMSD 0.37 Å
- 8K2C chain Ln against the predicted model P62945: TM-score 0.89, RMSD 0.33 Å
- 8G5Z chain Ln against the predicted model P62945: TM-score 0.89, RMSD 0.34 Å
- 8JDK chain s against the predicted model P62945: TM-score 0.89, RMSD 0.34 Å
- 7XNY chain Ln against the predicted model P62945: TM-score 0.89, RMSD 0.34 Å
- 6ZMO chain Ln against the predicted model P62945: TM-score 0.88, RMSD 0.36 Å
- 8JDJ chain s against the predicted model P62945: TM-score 0.88, RMSD 0.35 Å
- 8G60 chain Ln against the predicted model P62945: TM-score 0.87, RMSD 0.39 Å
- 8GLP chain Ln against the predicted model P62945: TM-score 0.87, RMSD 0.40 Å
- 6Z6L chain Ln against the predicted model P62945: TM-score 0.87, RMSD 0.39 Å
Elsewhere
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