UniProt P62906
60S ribosomal protein L10a (P62906)
60S ribosomal protein L10a (UniProt P62906): 31 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62906
- Protein
- 60S ribosomal protein L10a
- Experimental structures
- 31
- Predicted models
- 1
- Pockets
- 3 · 3 records with a druggable one
Structures
32 records of P62906 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UG0 | Structure of the human 80S ribosome | electron microscopy | Lz | — | — |
| 4V6X | Structure of the human 80S ribosome | electron microscopy | Cz | — | — |
| 5LKS | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | electron microscopy | Lz | — | — |
| 6LQM | Cryo-EM structure of a pre-60S ribosomal subunit - state C | electron microscopy | A | — | — |
| 6LU8 | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | electron microscopy | A | — | — |
| 6QZP | High-resolution cryo-EM structure of the human 80S ribosome | electron microscopy | Lz | — | — |
| 6Y6X | Tetracenomycin X bound to the human ribosome | electron microscopy | Lz | — | — |
| 6Z6L | Cryo-EM structure of human CCDC124 bound to 80S ribosomes | electron microscopy | Lz | — | — |
| 6ZMO | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | electron microscopy | Lz | — | 1 (best 0.88) |
| 8FKU | Human nucleolar pre-60S ribosomal subunit (State C2) | electron microscopy | BB | — | — |
| 8FKV | Human nucleolar pre-60S ribosomal subunit (State D1) | electron microscopy | BB | — | — |
| 8FKW | Human nucleolar pre-60S ribosomal subunit (State D2) | electron microscopy | BB | — | — |
| 8FKX | Human nucleolar pre-60S ribosomal subunit (State E) | electron microscopy | BB | — | — |
| 8FL2 | Human nuclear pre-60S ribosomal subunit (State I1) | electron microscopy | BB | — | — |
| 8FL3 | Human nuclear pre-60S ribosomal subunit (State I2) | electron microscopy | BB | — | — |
| 8FL4 | Human nuclear pre-60S ribosomal subunit (State I3) | electron microscopy | BB | — | — |
| 8G5Y | mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) | electron microscopy | Lz | — | — |
| 8G60 | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | electron microscopy | Lz | — | 1 (best 0.87) |
| 8G61 | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | electron microscopy | Lz | — | — |
| 8IDY | human nuclear pre-60S ribosomal particle - State F | electron microscopy | t | — | — |
| 8IFD | Dibekacin-added human 80S ribosome | electron microscopy | 2l | — | — |
| 8INF | human nuclear pre-60S ribosomal particle - State F' | electron microscopy | q | — | — |
| 8K2C | Cryo-EM structure of the human 80S ribosome with Tigecycline | electron microscopy | Lz | — | — |
| 8OHD | 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) | electron microscopy | Lz | — | — |
| 8OJ5 | 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution) | electron microscopy | Lz | — | — |
| 8OJ8 | 60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) | electron microscopy | Lz | — | — |
| 8UKB | In situ HHT and CHX treated human hibernating state without E-tRNA 80S ribosome | electron microscopy | Lz | — | — |
| 8XSX | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | electron microscopy | Lz | — | — |
| 8XSY | Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head… | electron microscopy | Lz | — | — |
| 8Y0W | dormant ribosome with eIF5A, eEF2 and SERBP1 | electron microscopy | Lz | — | — |
| 8YOP | Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline | electron microscopy | Lz | — | — |
| P62906 | AlphaFold monomer V2.0 prediction for 60S ribosomal protein L10A (P62906) | predicted | A | — | 1 (best 0.58) |
Experiment against prediction
- 8FKX chain BB against the predicted model P62906: TM-score 0.99, RMSD 0.67 Å
- 8IDY chain t against the predicted model P62906: TM-score 0.98, RMSD 0.73 Å
- 8INF chain q against the predicted model P62906: TM-score 0.98, RMSD 0.79 Å
- 8FKW chain BB against the predicted model P62906: TM-score 0.98, RMSD 0.80 Å
- 8FKV chain BB against the predicted model P62906: TM-score 0.98, RMSD 0.82 Å
- 8FKU chain BB against the predicted model P62906: TM-score 0.97, RMSD 0.99 Å
- 8Y0W chain Lz against the predicted model P62906: TM-score 0.96, RMSD 1.11 Å
- 8FL2 chain BB against the predicted model P62906: TM-score 0.95, RMSD 1.50 Å
- 8FL3 chain BB against the predicted model P62906: TM-score 0.95, RMSD 1.51 Å
- 8FL4 chain BB against the predicted model P62906: TM-score 0.95, RMSD 1.52 Å
Elsewhere
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