UniProt P62881
Guanine nucleotide-binding protein subunit beta-5 (P62881)
Guanine nucleotide-binding protein subunit beta-5 (UniProt P62881): 6 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62881
- Protein
- Guanine nucleotide-binding protein subunit beta-5
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 11 · 2 records with a druggable one
Structures
7 records of P62881 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2PBI | The multifunctional nature of Gbeta5/RGS9 revealed from its crystal structure | x-ray diffraction | B, D | — | — |
| 2PBI | The multifunctional nature of GBETA5/RGS9 revealed from its crystal structure | x-ray diffraction | B, D | — | — |
| 6N9G | Crystal Structure of RGS7-Gbeta5 dimer | x-ray diffraction | C, D | — | — |
| 6N9G | Crystal structure of RGS7-GBETA5 dimer | x-ray diffraction | C, D | — | — |
| 7SHF | Cryo-EM structure of GPR158 coupled to the RGS7-Gbeta5 complex | electron microscopy | D | — | 7 (best 0.86) |
| 7SHF | Cryo-EM structure of GPR158 coupled to the RGS7-GBETA5 complex | electron microscopy | D | — | — |
| P62881 | AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein subunit beta-5 (P62881) | predicted | A | — | 4 (best 0.79) |
Experiment against prediction
- 2PBI chain D against the predicted model P62881: TM-score 0.99, RMSD 0.75 Å
- 2PBI chain D against the predicted model P62881: TM-score 0.99, RMSD 0.75 Å
- 2PBI chain B against the predicted model P62881: TM-score 0.99, RMSD 0.90 Å
- 2PBI chain B against the predicted model P62881: TM-score 0.99, RMSD 0.90 Å
- 7SHF chain D against the predicted model P62881: TM-score 0.95, RMSD 2.04 Å
- 7SHF chain D against the predicted model P62881: TM-score 0.95, RMSD 2.04 Å
- 6N9G chain D against the predicted model P62881: TM-score 0.94, RMSD 1.85 Å
- 6N9G chain D against the predicted model P62881: TM-score 0.94, RMSD 1.85 Å
- 6N9G chain C against the predicted model P62881: TM-score 0.94, RMSD 1.99 Å
- 6N9G chain C against the predicted model P62881: TM-score 0.94, RMSD 1.99 Å
Elsewhere
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