UniProt P62807
Histone H2B type 1-C/E/F/G/I (P62807)
Histone H2B type 1-C/E/F/G/I (UniProt P62807): 49 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 175 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62807
- Protein
- Histone H2B type 1-C/E/F/G/I
- Experimental structures
- 49
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 175 · 18 records with a druggable one
Structures
50 records of P62807 in the MolNFT archive: 49 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GT0 | Crystal structure of nucleosome complex with human testis-specific histone variants, Th2a | x-ray diffraction | D, H | MN | 12 (best 0.80) |
| 5GT0 | Crystal structure of nucleosome complex with human testis-specific histone variants, TH2A | x-ray diffraction | D, H | — | — |
| 5KGF | Structural model of 53BP1 bound to a ubiquitylated and methylated nucleosome, at 4.5 A resolution | electron microscopy | D, H | — | 13 (best 0.78) |
| 5KGF | Structural model of 53BP1 bound to a ubiquitylated and methylated nucleosome, at 4.5 a resolution | electron microscopy | D, H | — | — |
| 6C0W | Cryo-EM structure of human kinetochore protein CENP-N with the centromeric nucleosome containing… | electron microscopy | D, H | — | 10 (best 0.84) |
| 6C0W | Cryo-EM structure of human kinetochore protein cenp-N with the centromeric nucleosome containing… | electron microscopy | D, H | — | — |
| 6FML | Cryoem structure INO80CORE nucleosome complex | electron microscopy | P, T | — | — |
| 6R0C | Human-D02 nucleosome core particle with biotin-streptavidin label | electron microscopy | D, H | — | — |
| 6RNY | Pfv intasome - nucleosome strand transfer complex | electron microscopy | D, H | — | — |
| 6SE0 | Class 1 : CENP-A nucleosome | electron microscopy | D, H | — | 11 (best 0.80) |
| 6SE0 | Class 1 : cenp-a nucleosome | electron microscopy | D, H | — | — |
| 6SE6 | Class2 : CENP-A nucleosome in complex with CENP-C central region | electron microscopy | D, H | — | — |
| 6SE6 | CLASS2 : cenp-a nucleosome in complex with cenp-C central region | electron microscopy | D, H | — | — |
| 6SEE | CLASS2A : cenp-a nucleosome in complex with cenp-C central region | electron microscopy | D, H | — | — |
| 6SEF | CLASS2C : cenp-a nucleosome in complex with cenp-C central region | electron microscopy | D, H | — | — |
| 6SEG | CLASS1: cenp-a nucleosome in complex with cenp-C central region | electron microscopy | D, H | — | — |
| 6UPK | Structure of FACT_SUBNUCLEOSOME complex 1 | electron microscopy | D | — | — |
| 6UPL | Structure of FACT_SUBNUCLEOSOME complex 2 | electron microscopy | D, L | — | — |
| 6X59 | The mouse cgas catalytic domain binding to human assembled nucleosome | electron microscopy | D, H | — | — |
| 6X5A | The mouse cgas catalytic domain binding to human nucleosome that purified from HEK293T cells | electron microscopy | D, H | — | — |
| 6XJD | Two mouse cGAS catalytic domain binding to human assembled nucleosome | electron microscopy | D, H | — | — |
| 6XJD | Two mouse cgas catalytic domain binding to human assembled nucleosome | electron microscopy | D, H | — | — |
| 7A08 | Cryoem structure of cgas nucleosome complex | electron microscopy | c, g | — | — |
| 7JO9 | 1:1 cgas-nucleosome complex | electron microscopy | D, H | — | — |
| 7JOA | 2:1 cgas-nucleosome complex | electron microscopy | D, H | — | — |
| 7PII | Structure of the human ccan cenp-a alpha-satellite complex | electron microscopy | D, H | — | — |
| 7R5R | Structure of the human ccan cenp-a alpha-satellite complex | electron microscopy | D, H | — | — |
| 7TAN | Structure of VRK1 C-terminal tail bound to nucleosome core particle | electron microscopy | D, H | — | 10 (best 0.75) |
| 7TAN | Structure of VRK1 C-terminal tail bound to nucleosome core particle | electron microscopy | D, H | — | — |
| 7TRF | Human telomerase catalytic core rnp with H2A/H2B | electron microscopy | F | — | — |
| 7U46 | Cryo-EM structure of cenp-a nucleosome (palindromic alpha satellite DNA) in complex with cenp-N | electron microscopy | D, H | — | — |
| 7U47 | Cryoem structure of cenp-N promoted nucleosome stacks with cenp-a and palindromic alpha satellite… | electron microscopy | D, H, O, S | — | — |
| 7U4D | Cryoem structure of cenp-N promoted nucleosome stacks with cenp-a and 601 DNA sequence | electron microscopy | D, H, O, S | — | — |
| 7U51 | Nucleosome core particle with AP-site at SHL-6 | electron microscopy | D, H | — | 10 (best 0.79) |
| 7U52 | nucleosome core particle with AP-site at SHL-6.5 | electron microscopy | D, H | — | 13 (best 0.82) |
| 7U53 | Nucleosome core particle with AP-site at SHL0 | electron microscopy | D, H | — | 12 (best 0.80) |
| 7YWX | Structure of the human CCAN CENP-A alpha-satellite complex | electron microscopy | D, V | — | — |
| 7YWX | Structure of the human ccan cenp-a alpha-satellite complex | electron microscopy | D, V | — | — |
| 7YYH | Structure of the human CCANdeltaT CENP-A alpha-satellite complex | electron microscopy | D, h | — | 2 (best 0.81) |
| 7YYH | Structure of the human ccandeltat cenp-a alpha-satellite complex | electron microscopy | D, h | — | — |
| 8OOA | CryoEM Structure INO80core Hexasome complex Hexasome refinement state1 | electron microscopy | P | — | 7 (best 0.79) |
| 8OX1 | Structure of TRF1core in complex with telomeric nucleosome | electron microscopy | D, H | — | 10 (best 0.77) |
| 8QZM | Structure of DNMT3A1 UDR region bound to H2AK119ub nucleosome | electron microscopy | D, H | — | 11 (best 0.77) |
| 8TXW | Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex… | electron microscopy | D, H | — | 11 (best 0.77) |
| 8TXX | Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex… | electron microscopy | D, H | — | 10 (best 0.78) |
| 8VWT | OGG1 bound to a nucleosome containing 8oxoG at SHL-6 (composite map) | electron microscopy | H, D | — | 12 (best 0.80) |
| 8VWV | OGG1 bound to a nucleosome containing 8oxoG at SHL4 (composite map) | electron microscopy | D, H | — | 10 (best 0.79) |
| 8X15 | Structure of nucleosome-bound SRCAP-C in the apo state | electron microscopy | B, F | — | 1 (best 0.82) |
| 9EOZ | Human OGG1 bound to a nucleosome core particle with 8-oxodGuo lesion at SHL6.0 | electron microscopy | H, M | — | 10 (best 0.79) |
| P62807 | AlphaFold monomer V2.0 prediction for histone H2B type 1-C/E/F/G/I (P62807) | predicted | A | — | — |
Ligands
- MN · Manganese (II) ion · in 1 record
Experiment against prediction
- 7U52 chain D against the predicted model P62807: TM-score 0.91, RMSD 1.32 Å
- 6SEG chain H against the predicted model P62807: TM-score 0.90, RMSD 1.36 Å
- 7PII chain D against the predicted model P62807: TM-score 0.90, RMSD 1.47 Å
- 7YYH chain D against the predicted model P62807: TM-score 0.90, RMSD 1.47 Å
- 7YYH chain D against the predicted model P62807: TM-score 0.90, RMSD 1.47 Å
- 7A08 chain g against the predicted model P62807: TM-score 0.90, RMSD 1.48 Å
- 7YYH chain h against the predicted model P62807: TM-score 0.90, RMSD 1.51 Å
- 7YYH chain h against the predicted model P62807: TM-score 0.90, RMSD 1.51 Å
- 7PII chain H against the predicted model P62807: TM-score 0.90, RMSD 1.51 Å
- 7U51 chain H against the predicted model P62807: TM-score 0.90, RMSD 1.41 Å
Elsewhere
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