UniProt P62487
DNA-directed RNA polymerase II subunit RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (UniProt P62487): 22 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62487
- Protein
- DNA-directed RNA polymerase II subunit RPB7
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 4 · 4 records with a druggable one
Structures
23 records of P62487 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2C35 | Subunits Rpb4 and Rpb7 of human RNA polymerase II | x-ray diffraction | B, D, F, H | — | — |
| 2C35 | Subunits RPB4 and RPB7 of human RNA polymerase II | x-ray diffraction | B, D, F, H | — | — |
| 5IY6 | Human holo-PIC in the closed state | electron microscopy | G | — | 1 (best 0.80) |
| 5IY6 | Human holo-pic in the closed state | electron microscopy | G | — | — |
| 5IY7 | Human holo-PIC in the open state | electron microscopy | G | — | — |
| 5IY7 | Human holo-pic in the open state | electron microscopy | G | — | — |
| 5IY8 | Human holo-PIC in the initial transcribing state | electron microscopy | G | — | — |
| 5IY8 | Human holo-pic in the initial transcribing state | electron microscopy | G | — | — |
| 5IY9 | Human holo-PIC in the initial transcribing state (no IIS) | electron microscopy | G | — | — |
| 5IY9 | Human holo-pic in the initial transcribing state (no iis) | electron microscopy | G | — | — |
| 5IYA | Human core-PIC in the closed state | electron microscopy | G | — | — |
| 5IYA | Human core-pic in the closed state | electron microscopy | G | — | — |
| 5IYB | Human core-PIC in the open state | electron microscopy | G | — | 1 (best 0.78) |
| 5IYB | Human core-pic in the open state | electron microscopy | G | — | — |
| 5IYC | Human core-PIC in the initial transcribing state | electron microscopy | G | — | 1 (best 0.80) |
| 5IYC | Human core-pic in the initial transcribing state | electron microscopy | G | — | — |
| 5IYD | Human core-PIC in the initial transcribing state (no IIS) | electron microscopy | G | — | — |
| 5IYD | Human core-pic in the initial transcribing state (no iis) | electron microscopy | G | — | — |
| 6DRD | RNA Pol II(G) | electron microscopy | G | — | 1 (best 0.75) |
| 6DRD | RNA pol II(G) | electron microscopy | G | — | — |
| 6O9L | Human holo-pic in the closed state | electron microscopy | G | — | — |
| 6XRE | Structure of the P53/RNA polymerase II assembly | electron microscopy | G | — | — |
| P62487 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB7 (P62487) | predicted | A | — | — |
Experiment against prediction
- 5IY7 chain G against the predicted model P62487: TM-score 0.97, RMSD 0.90 Å
- 5IY7 chain G against the predicted model P62487: TM-score 0.97, RMSD 0.90 Å
- 5IYB chain G against the predicted model P62487: TM-score 0.97, RMSD 0.90 Å
- 5IYB chain G against the predicted model P62487: TM-score 0.97, RMSD 0.90 Å
- 5IY8 chain G against the predicted model P62487: TM-score 0.97, RMSD 0.91 Å
- 5IY8 chain G against the predicted model P62487: TM-score 0.97, RMSD 0.91 Å
- 5IYC chain G against the predicted model P62487: TM-score 0.97, RMSD 0.91 Å
- 5IYC chain G against the predicted model P62487: TM-score 0.97, RMSD 0.91 Å
- 5IY6 chain G against the predicted model P62487: TM-score 0.97, RMSD 0.93 Å
- 5IY6 chain G against the predicted model P62487: TM-score 0.97, RMSD 0.93 Å
Elsewhere
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