UniProt P62137
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (P62137)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (UniProt P62137), EC 3.1.3.16: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 36 pockets. Binding sites, druggability and experiment…
- UniProt
- P62137
- Protein
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- EC
- 3.1.3.16
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 36 · 3 records with a druggable one
Structures
5 records of P62137 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ZQV | Crystal Structure of Protein Phosphate 1 complexed with PP1 binding domain of GM | x-ray diffraction | A, B, C, D | MN | 15 (best 0.72) |
| 5ZQV | Crystal structure of protein phosphate 1 complexed with PP1 binding domain of gm | x-ray diffraction | A, B, C, D | MN | — |
| 5ZT0 | Crystal Structure of Protein Phosphate 1 Complexed with PP1 binding domain of GL | x-ray diffraction | A, B, C, D, E, F | MN, PO4 | 17 (best 0.77) |
| 5ZT0 | Crystal structure of protein phosphate 1 complexed with PP1 binding domain of gl | x-ray diffraction | A, B, C, D, E, F | MN, PO4 | — |
| P62137 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase PP1-alpha catalytic… | predicted | A | — | 4 (best 0.65) |
Ligands
Experiment against prediction
- 5ZQV chain A against the predicted model P62137: TM-score 1.00, RMSD 0.46 Å
- 5ZQV chain A against the predicted model P62137: TM-score 1.00, RMSD 0.46 Å
- 5ZT0 chain A against the predicted model P62137: TM-score 1.00, RMSD 0.45 Å
- 5ZT0 chain A against the predicted model P62137: TM-score 1.00, RMSD 0.45 Å
- 5ZQV chain B against the predicted model P62137: TM-score 1.00, RMSD 0.47 Å
- 5ZQV chain B against the predicted model P62137: TM-score 1.00, RMSD 0.47 Å
- 5ZT0 chain E against the predicted model P62137: TM-score 0.99, RMSD 0.46 Å
- 5ZT0 chain D against the predicted model P62137: TM-score 0.99, RMSD 0.47 Å
- 5ZT0 chain C against the predicted model P62137: TM-score 0.99, RMSD 0.47 Å
- 5ZQV chain D against the predicted model P62137: TM-score 0.99, RMSD 0.49 Å
Elsewhere
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