UniProt P61926
P61926
P61926 (UniProt P61926): 25 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P61926
- Experimental structures
- 25
- Predicted models
- 1
- Ligands
- 1
Structures
26 records of P61926 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FMO | Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of camp-dependent protein… | x-ray diffraction | I | — | — |
| 1FMO | Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of camp-dependent protein… | x-ray diffraction | I | — | — |
| 2ERZ | Crystal Structure of c-AMP Dependent Kinase (PKA) bound to hydroxyfasudil | x-ray diffraction | I | — | — |
| 2ERZ | Crystal structure of C-AMP dependent kinase (PKA) bound to hydroxyfasudil | x-ray diffraction | I | — | — |
| 2GFC | cAMP-dependent protein kinase PKA catalytic subunit with PKI-5-24 | x-ray diffraction | I | — | — |
| 2GFC | Camp-dependent protein kinase PKA catalytic subunit with pki-5-24 | x-ray diffraction | I | — | — |
| 2GNF | Protein kinase A fivefold mutant model of Rho-kinase with Y-27632 | x-ray diffraction | I | — | — |
| 2GNF | Protein kinase a fivefold mutant model of rho-kinase with Y-27632 | x-ray diffraction | I | — | — |
| 2GNG | Protein kinase A fivefold mutant model of Rho-kinase | x-ray diffraction | I | — | — |
| 2GNG | Protein kinase a fivefold mutant model of rho-kinase | x-ray diffraction | I | — | — |
| 2GNH | PKA five fold mutant model of Rho-kinase with H1152P | x-ray diffraction | I | — | — |
| 2GNH | PKA five fold mutant model of rho-kinase with H1152P | x-ray diffraction | I | — | — |
| 2GNI | PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077) | x-ray diffraction | I | — | — |
| 2GNI | PKA fivefold mutant model of rho-kinase with inhibitor fasudil (HA1077) | x-ray diffraction | I | — | — |
| 2GNJ | PKA three fold mutant model of Rho-kinase with Y-27632 | x-ray diffraction | I | — | — |
| 2GNJ | PKA three fold mutant model of rho-kinase with Y-27632 | x-ray diffraction | I | — | — |
| 2GNL | PKA threefold mutant model of Rho-kinase with inhibitor H-1152P | x-ray diffraction | I | — | — |
| 2GNL | PKA threefold mutant model of rho-kinase with inhibitor H-1152P | x-ray diffraction | I | — | — |
| 3DND | cAMP-dependent protein kinase PKA catalytic subunit with PKI-5-24 | x-ray diffraction | I | — | — |
| 3DND | Camp-dependent protein kinase PKA catalytic subunit with pki-5-24 | x-ray diffraction | I | — | — |
| 3DNE | cAMP-dependent protein kinase PKA catalytic subunit with PKI-5-24 | x-ray diffraction | I | — | — |
| 3DNE | Camp-dependent protein kinase PKA catalytic subunit with pki-5-24 | x-ray diffraction | I | — | — |
| 4YXS | Camp-dependent protein kinase PKA catalytic subunit with pki-5-24 | x-ray diffraction | I | — | — |
| 4YXS | Camp-dependent protein kinase PKA catalytic subunit with pki-5-24 | x-ray diffraction | I | — | — |
| 5UZK | Crystal structure of PKA bound to an pyrrolo pyridine inhibitor | x-ray diffraction | I | 504 | — |
| P61926 | AlphaFold monomer V2.0 prediction for camp-dependent protein kinase inhibitor alpha (P61926) | predicted | A | — | — |
Ligands
- 504 · 2-{3-[3-(piperidin-4-yl)propoxy]phenyl}-N-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]acetamide · in 1 record
Experiment against prediction
- 5UZK chain I against the predicted model P61926: TM-score 0.45, RMSD 1.29 Å
- 4YXS chain I against the predicted model P61926: TM-score 0.41, RMSD 2.09 Å
- 4YXS chain I against the predicted model P61926: TM-score 0.41, RMSD 2.09 Å
- 2GNI chain I against the predicted model P61926: TM-score 0.41, RMSD 1.33 Å
- 2GNI chain I against the predicted model P61926: TM-score 0.41, RMSD 1.33 Å
- 2GNG chain I against the predicted model P61926: TM-score 0.41, RMSD 2.16 Å
- 2GNG chain I against the predicted model P61926: TM-score 0.41, RMSD 2.16 Å
- 2GFC chain I against the predicted model P61926: TM-score 0.40, RMSD 2.14 Å
- 2GFC chain I against the predicted model P61926: TM-score 0.40, RMSD 2.14 Å
- 3DNE chain I against the predicted model P61926: TM-score 0.40, RMSD 1.72 Å
Elsewhere
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