UniProt P61160
Actin-related protein 2 (P61160)
Actin-related protein 2 (UniProt P61160): 7 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P61160
- Protein
- Actin-related protein 2
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 3 records with a druggable one
Structures
8 records of P61160 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6UHC | CryoEM structure of human Arp2/3 complex with bound NPFs | electron microscopy | B | MG, ATP | 6 (best 0.83) |
| 6UHC | Cryoem structure of human ARP2/3 complex with bound npfs | electron microscopy | B | MG, ATP | — |
| 6YW6 | Cryo-EM structure of the ARP2/3 1B5CL isoform complex. | electron microscopy | B | ATP | 5 (best 0.79) |
| 6YW6 | Cryo-EM structure of the ARP2/3 1B5CL isoform complex. | electron microscopy | B | ATP | — |
| 6YW7 | Cryo-EM structure of the ARP2/3 1A5C isoform complex. | electron microscopy | B | ATP | 4 (best 0.49) |
| 6YW7 | Cryo-EM structure of the ARP2/3 1A5C isoform complex. | electron microscopy | B | ATP | — |
| 8P94 | Cryo-EM structure of cortactin stabilized Arp2/3-complex nucleated actin branches | electron microscopy | B | ADP, MG | 5 (best 0.88) |
| P61160 | AlphaFold monomer V2.0 prediction for actin-related protein 2 (P61160) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8P94 chain B against the predicted model P61160: TM-score 0.95, RMSD 1.90 Å
- 6YW7 chain B against the predicted model P61160: TM-score 0.91, RMSD 2.41 Å
- 6YW7 chain B against the predicted model P61160: TM-score 0.91, RMSD 2.41 Å
- 6YW6 chain B against the predicted model P61160: TM-score 0.90, RMSD 2.37 Å
- 6YW6 chain B against the predicted model P61160: TM-score 0.90, RMSD 2.37 Å
- 6UHC chain B against the predicted model P61160: TM-score 0.90, RMSD 2.54 Å
- 6UHC chain B against the predicted model P61160: TM-score 0.90, RMSD 2.54 Å
Elsewhere
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