UniProt P60901
Proteasome subunit alpha type-6 (P60901)
Proteasome subunit alpha type-6 (UniProt P60901), EC 3.4.25.1: 10 experimental structures and 1 predicted model on GenesisL1, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P60901
- Protein
- Proteasome subunit alpha type-6
- EC
- 3.4.25.1
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 18 · 5 records with a druggable one
Structures
11 records of P60901 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6EPC | Ground state 26S proteasome (GS2) | electron microscopy | A | — | 4 (best 0.88) |
| 6EPC | Ground state 26S proteasome (GS2) | electron microscopy | A | — | — |
| 6EPD | Substrate processing state 26S proteasome (SPS1) | electron microscopy | A | — | 3 (best 0.81) |
| 6EPD | Substrate processing state 26S proteasome (SPS1) | electron microscopy | A | — | — |
| 6EPE | Substrate processing state 26S proteasome (SPS2) | electron microscopy | A | — | 1 (best 0.86) |
| 6EPE | Substrate processing state 26S proteasome (SPS2) | electron microscopy | A | — | — |
| 6EPF | Ground state 26S proteasome (GS1) | electron microscopy | A | — | 3 (best 0.87) |
| 6EPF | Ground state 26S proteasome (GS1) | electron microscopy | A | — | — |
| 6TU3 | Rat 20S proteasome | electron microscopy | A, O | — | 6 (best 0.77) |
| 6TU3 | Rat 20S proteasome | electron microscopy | A, O | — | — |
| P60901 | AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-6 (P60901) | predicted | A | — | 1 (best 0.33) |
Experiment against prediction
- 6TU3 chain A against the predicted model P60901: TM-score 0.97, RMSD 0.91 Å
- 6TU3 chain A against the predicted model P60901: TM-score 0.97, RMSD 0.91 Å
- 6TU3 chain O against the predicted model P60901: TM-score 0.97, RMSD 0.91 Å
- 6EPF chain A against the predicted model P60901: TM-score 0.93, RMSD 1.74 Å
- 6EPF chain A against the predicted model P60901: TM-score 0.93, RMSD 1.74 Å
- 6EPC chain A against the predicted model P60901: TM-score 0.93, RMSD 1.84 Å
- 6EPC chain A against the predicted model P60901: TM-score 0.93, RMSD 1.84 Å
- 6EPD chain A against the predicted model P60901: TM-score 0.92, RMSD 1.88 Å
- 6EPD chain A against the predicted model P60901: TM-score 0.92, RMSD 1.88 Å
- 6EPE chain A against the predicted model P60901: TM-score 0.92, RMSD 1.83 Å
Elsewhere
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