UniProt P60712
Actin, cytoplasmic 1, N-terminally processed (P60712)
Actin, cytoplasmic 1, N-terminally processed (UniProt P60712): 14 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 51 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P60712
- Protein
- Actin, cytoplasmic 1, N-terminally processed
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 51 · 3 records with a druggable one
Structures
15 records of P60712 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HLU | Structure of bovine beta-actin-profilin complex with actin bound ATP phosphates solvent accessible | x-ray diffraction | A | — | — |
| 1HLU | Structure of bovine beta-actin-profilin complex with actin bound ATP phosphates solvent accessible | x-ray diffraction | A | — | — |
| 2BTF | The structure of crystalline profilin-beta-actin | x-ray diffraction | A | — | — |
| 2BTF | The structure of crystalline profilin-beta-actin | x-ray diffraction | A | — | — |
| 2OAN | Structure of oxidized beta-actin | x-ray diffraction | A, B, C, D | — | — |
| 2OAN | Structure of oxidized beta-actin | x-ray diffraction | A, B, C, D | — | — |
| 3U4L | Cryocooled bovine profilin:actin crystal structure to 2.4 A | x-ray diffraction | A | — | — |
| 3U4L | Cryocooled bovine PROFILIN:ACTIN crystal structure to 2.4 a | x-ray diffraction | A | — | — |
| 3UB5 | Profilin:actin with a wide open nucleotide cleft | x-ray diffraction | A | — | — |
| 3UB5 | PROFILIN:ACTIN with a wide open nucleotide cleft | x-ray diffraction | A | — | — |
| 7PDZ | Structure of capping protein bound to the barbed end of a cytoplasmic actin filament | electron microscopy | I, J, K, L, N, O | ADP, MG, PO4 | 16 (best 0.84) |
| 7PDZ | Structure of capping protein bound to the barbed end of a cytoplasmic actin filament | electron microscopy | I, J, K, L, N, O | ADP, MG, PO4 | — |
| 9FJU | Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 1) | electron microscopy | A, B, C, D | ADP, MG, PO4 | 17 (best 0.87) |
| 9FJY | Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 2). | electron microscopy | A, B, C, D | ADP, MG, PO4 | 18 (best 0.85) |
| P60712 | AlphaFold monomer V2.0 prediction for actin, cytoplasmic 1 (P60712) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3U4L chain A against the predicted model P60712: TM-score 0.98, RMSD 1.00 Å
- 3U4L chain A against the predicted model P60712: TM-score 0.98, RMSD 1.00 Å
- 2BTF chain A against the predicted model P60712: TM-score 0.97, RMSD 1.33 Å
- 2BTF chain A against the predicted model P60712: TM-score 0.97, RMSD 1.33 Å
- 2OAN chain A against the predicted model P60712: TM-score 0.97, RMSD 1.21 Å
- 2OAN chain A against the predicted model P60712: TM-score 0.97, RMSD 1.21 Å
- 2OAN chain B against the predicted model P60712: TM-score 0.97, RMSD 1.34 Å
- 2OAN chain B against the predicted model P60712: TM-score 0.97, RMSD 1.34 Å
- 2OAN chain D against the predicted model P60712: TM-score 0.97, RMSD 1.38 Å
- 2OAN chain D against the predicted model P60712: TM-score 0.97, RMSD 1.38 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.