UniProt P60059
Protein transport protein Sec61 subunit gamma (P60059)
Protein transport protein Sec61 subunit gamma (UniProt P60059): 6 experimental structures and 1 predicted model on GenesisL1, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P60059
- Protein
- Protein transport protein Sec61 subunit gamma
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 19 · 5 records with a druggable one
Structures
7 records of P60059 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8DNW | Cryo-EM structure of the human Sec61 complex in a partially-open apo state (Class 2) | electron microscopy | B | — | 5 (best 0.70) |
| 8DNY | Cryo-EM structure of the human Sec61 complex inhibited by decatransin | electron microscopy | B | — | — |
| 8DNZ | Cryo-EM structure of the human Sec61 complex inhibited by apratoxin F | electron microscopy | B | — | 5 (best 0.69) |
| 8DO1 | Cryo-EM structure of the human Sec61 complex inhibited by ipomoeassin F | electron microscopy | B | — | 4 (best 0.55) |
| 8DO3 | Cryo-EM structure of the human Sec61 complex inhibited by eeyarestatin I | electron microscopy | B | — | 4 (best 0.75) |
| 8OJ8 | 60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) | electron microscopy | 2 | — | 1 (best 0.87) |
| P60059 | AlphaFold monomer V2.0 prediction for protein transport protein SEC61 subunit gamma (P60059) | predicted | A | — | — |
Experiment against prediction
- 8DO1 chain B against the predicted model P60059: TM-score 0.93, RMSD 0.78 Å
- 8DNY chain B against the predicted model P60059: TM-score 0.91, RMSD 0.85 Å
- 8DNW chain B against the predicted model P60059: TM-score 0.90, RMSD 0.94 Å
- 8DNZ chain B against the predicted model P60059: TM-score 0.90, RMSD 0.95 Å
- 8DO3 chain B against the predicted model P60059: TM-score 0.89, RMSD 0.97 Å
- 8OJ8 chain 2 against the predicted model P60059: TM-score 0.84, RMSD 1.30 Å
Elsewhere
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