UniProt P60058
Protein transport protein Sec61 subunit gamma (P60058)
Protein transport protein Sec61 subunit gamma (UniProt P60058): 17 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P60058
- Protein
- Protein transport protein Sec61 subunit gamma
- Experimental structures
- 17
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
18 records of P60058 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2WWB | Cryo-EM structure of the mammalian SEC61 complex bound to the actively translating wheat germ 80S… | electron microscopy | B | — | — |
| 2WWB | Cryo-EM structure of the mammalian SEC61 complex bound to the actively translating wheat germ 80S… | electron microscopy | B | — | — |
| 3JC2 | The structure of the mammalian Sec61 channel opened by a signal sequence | electron microscopy | 2 | — | — |
| 3JC2 | The structure of the mammalian SEC61 channel opened by a signal sequence | electron microscopy | 2 | — | — |
| 4CG5 | Cryo-EM of the Sec61-complex bound to the 80S ribosome translating a secretory substrate | electron microscopy | B | — | — |
| 4CG5 | Cryo-EM of the SEC61-complex bound to the 80S ribosome translating a secretory substrate | electron microscopy | B | — | — |
| 4CG6 | Cryo-em of the Sec61-complex bound to the 80s ribosome translating a membrane-inserting substrate | electron microscopy | B | — | — |
| 4CG6 | Cryo-EM of the SEC61-complex bound to the 80S ribosome translating a membrane-inserting substrate | electron microscopy | B | — | — |
| 4CG7 | Cryo-EM of the Sec61-complex bound to the idle 80S ribosome | electron microscopy | B | — | — |
| 4CG7 | Cryo-EM of the SEC61-complex bound to the idle 80S ribosome | electron microscopy | B | — | — |
| 5A6U | Native mammalian ribosome-bound Sec61 protein-conducting channel in the 'non-inserting' state | electron microscopy | G | — | — |
| 5A6U | Native mammalian ribosome-bound SEC61 protein-conducting channel in the 'non-inserting' state | electron microscopy | G | — | — |
| 6FTJ | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Non-programmed… | electron microscopy | y | — | — |
| 6Z3T | Structure of canine SEC61 inhibited by mycolactone | electron microscopy | B | — | — |
| 8BTK | Structure of the TRAP complex with the Sec translocon and a translating ribosome | electron microscopy | SY | — | — |
| 8RJB | Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with… | electron microscopy | 3 | — | — |
| 8RJD | Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with… | electron microscopy | 3 | — | 1 (best 0.85) |
| P60058 | AlphaFold monomer V2.0 prediction for protein transport protein SEC61 subunit gamma (P60058) | predicted | A | — | — |
Experiment against prediction
- 6FTJ chain y against the predicted model P60058: TM-score 0.88, RMSD 1.08 Å
- 8RJB chain 3 against the predicted model P60058: TM-score 0.88, RMSD 1.42 Å
- 8BTK chain SY against the predicted model P60058: TM-score 0.87, RMSD 1.15 Å
- 6Z3T chain B against the predicted model P60058: TM-score 0.84, RMSD 1.21 Å
- 8RJD chain 3 against the predicted model P60058: TM-score 0.79, RMSD 1.95 Å
- 5A6U chain G against the predicted model P60058: TM-score 0.73, RMSD 2.10 Å
- 5A6U chain G against the predicted model P60058: TM-score 0.73, RMSD 2.10 Å
- 3JC2 chain 2 against the predicted model P60058: TM-score 0.66, RMSD 2.10 Å
- 3JC2 chain 2 against the predicted model P60058: TM-score 0.66, RMSD 2.10 Å
- 2WWB chain B against the predicted model P60058: TM-score 0.61, RMSD 2.39 Å
Elsewhere
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