UniProt P59997
Lysine-specific demethylase 2A (P59997)
Lysine-specific demethylase 2A (UniProt P59997): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P59997
- Protein
- Lysine-specific demethylase 2A
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 8 · 1 record with a druggable one
Structures
4 records of P59997 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4TN7 | Crystal structure of mouse KDM2A-H3K36ME-NO complex | x-ray diffraction | A, B, C, D | — | — |
| 4TN7 | Crystal structure of mouse KDM2A-H3K36ME-no complex | x-ray diffraction | A, B, C, D | — | — |
| 7UVA | Crystal structure of KDM2A histone demethylase catalytic domain in complex with an H3C36 peptide… | x-ray diffraction | A, B, D, E | FE, OH0 | — |
| P59997 | AlphaFold monomer V2.0 prediction for lysine-specific demethylase 2A (P59997) | predicted | A | — | 8 (best 0.78) |
Ligands
Experiment against prediction
- 7UVA chain A against the predicted model P59997: TM-score 1.00, RMSD 0.33 Å
- 4TN7 chain A against the predicted model P59997: TM-score 1.00, RMSD 0.34 Å
- 4TN7 chain A against the predicted model P59997: TM-score 1.00, RMSD 0.34 Å
- 7UVA chain B against the predicted model P59997: TM-score 0.97, RMSD 0.55 Å
- 4TN7 chain B against the predicted model P59997: TM-score 0.96, RMSD 0.60 Å
- 4TN7 chain B against the predicted model P59997: TM-score 0.96, RMSD 0.60 Å
Elsewhere
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