UniProt P59259
Histone H4 (P59259)
Histone H4 (UniProt P59259): 10 experimental structures and 1 predicted model on GenesisL1, 99 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P59259
- Protein
- Histone H4
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 99 · 10 records with a druggable one
Structures
11 records of P59259 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8J90 | Cryo-EM structure of DDM1-nucleosome complex | electron microscopy | B, F | — | 11 (best 0.83) |
| 8J91 | Cryo-EM structure of nucleosome containing Arabidopsis thaliana histones | electron microscopy | B, F | — | 11 (best 0.79) |
| 8J92 | Cryo-EM structure of nucleosome containing Arabidopsis thaliana H2A.W | electron microscopy | B, F | — | 11 (best 0.76) |
| 8KCB | Complex of DDM1-nucleosome(H2A) complex with DDM1 bound to SHL2 | electron microscopy | H, G | — | 8 (best 0.64) |
| 8KCC | Complex of DDM1-nucleosome(H2A.W) complex with DDM1 bound to SHL2 | electron microscopy | G, H | — | 11 (best 0.74) |
| 8WH5 | Structure of DDM1-nucleosome complex in the apo state | electron microscopy | B, F | — | 9 (best 0.77) |
| 8WH8 | Structure of DDM1-nucleosome complex in ADP state | electron microscopy | B, F | — | 10 (best 0.70) |
| 8WH9 | Structure of DDM1-nucleosome complex in ADP-BeFx state | electron microscopy | B, F | — | 9 (best 0.86) |
| 8WHA | Structure of DDM1-nucleosome complex in the ADP-BeFx state with DDM1 bound to SHL2 and SHL-2 | electron microscopy | B, F | — | 9 (best 0.86) |
| 8WHB | Structure of nucleosome core particle of Arabidopsis thaliana | electron microscopy | B, F | — | 10 (best 0.77) |
| P59259 | AlphaFold monomer V2.0 prediction for histone H4 (P59259) | predicted | A | — | — |
Experiment against prediction
- 8KCB chain G against the predicted model P59259: TM-score 0.94, RMSD 0.83 Å
- 8WHB chain F against the predicted model P59259: TM-score 0.94, RMSD 0.86 Å
- 8J90 chain B against the predicted model P59259: TM-score 0.93, RMSD 0.89 Å
- 8J91 chain F against the predicted model P59259: TM-score 0.93, RMSD 1.00 Å
- 8WH8 chain B against the predicted model P59259: TM-score 0.93, RMSD 1.04 Å
- 8WH9 chain B against the predicted model P59259: TM-score 0.93, RMSD 0.94 Å
- 8WH5 chain B against the predicted model P59259: TM-score 0.93, RMSD 1.05 Å
- 8WHB chain B against the predicted model P59259: TM-score 0.92, RMSD 0.99 Å
- 8J92 chain F against the predicted model P59259: TM-score 0.92, RMSD 1.05 Å
- 8KCC chain G against the predicted model P59259: TM-score 0.91, RMSD 1.20 Å
Elsewhere
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