UniProt P59078
Methionine--tRNA ligase (P59078)
Methionine--tRNA ligase (UniProt P59078), EC 6.1.1.10: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P59078
- Protein
- Methionine--tRNA ligase
- EC
- 6.1.1.10
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 25 · 3 records with a druggable one
Structures
3 records of P59078 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5K0S | Crystal structure of methionyl-tRNA synthetase metrs from brucella melitensis in complex with… | x-ray diffraction | A, B, C | 0OU | 13 (best 0.74) |
| 5K0T | Crystal structure of methionyl-tRNA synthetase metrs from brucella melitensis in complex with… | x-ray diffraction | A, B, C | 415 | 9 (best 0.68) |
| P59078 | AlphaFold monomer V2.0 prediction for methionine--tRNA ligase (P59078) | predicted | A | — | 3 (best 0.77) |
Ligands
Experiment against prediction
- 5K0T chain B against the predicted model P59078: TM-score 0.99, RMSD 0.80 Å
- 5K0T chain C against the predicted model P59078: TM-score 0.98, RMSD 1.26 Å
- 5K0S chain B against the predicted model P59078: TM-score 0.97, RMSD 1.60 Å
- 5K0S chain C against the predicted model P59078: TM-score 0.96, RMSD 2.15 Å
- 5K0T chain A against the predicted model P59078: TM-score 0.94, RMSD 2.15 Å
- 5K0S chain A against the predicted model P59078: TM-score 0.94, RMSD 2.19 Å
Elsewhere
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