UniProt P58717
4-hydroxythreonine-4-phosphate dehydrogenase 1 (P58717)
4-hydroxythreonine-4-phosphate dehydrogenase 1 (UniProt P58717), EC 1.1.1.262: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 7 pockets. Binding sites, druggability and experiment against…
- UniProt
- P58717
- Protein
- 4-hydroxythreonine-4-phosphate dehydrogenase 1
- EC
- 1.1.1.262
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 7 · 2 records with a druggable one
Structures
3 records of P58717 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1R8K | Pdxa protein; NAD-dependent DEHYDROGENASE/CARBOXYLASE; subunit of pyridoxine phosphate biosynthetic… | x-ray diffraction | A, B | CO, CL, SO4 | 5 (best 0.71) |
| 1R8K | Pdxa protein; NAD-dependent DEHYDROGENASE/CARBOXYLASE; subunit of pyridoxine phosphate biosynthetic… | x-ray diffraction | A, B | — | — |
| P58717 | AlphaFold monomer V2.0 prediction for 4-hydroxythreonine-4-phosphate dehydrogenase (P58717) | predicted | A | — | 2 (best 0.53) |
Ligands
Experiment against prediction
- 1R8K chain A against the predicted model P58717: TM-score 0.96, RMSD 1.39 Å
- 1R8K chain A against the predicted model P58717: TM-score 0.96, RMSD 1.39 Å
- 1R8K chain B against the predicted model P58717: TM-score 0.93, RMSD 1.87 Å
- 1R8K chain B against the predicted model P58717: TM-score 0.93, RMSD 1.87 Å
Elsewhere
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