UniProt P58032
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase (P58032)
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase (UniProt P58032), EC 2.1.1.-: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 51 pockets. Binding sites, druggability and experiment against…
- UniProt
- P58032
- Protein
- Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
- EC
- 2.1.1.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 51 · 4 records with a druggable one
Structures
7 records of P58032 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ID5 | Crystal structure of Sulfolobus solfataricus C/D RNP assembled with Nop5, fibrillarin, L7Ae and a… | x-ray diffraction | B, F | SAM | 9 (best 0.74) |
| 3ID5 | Crystal structure of sulfolobus solfataricus C/D rnp assembled with NOP5, fibrillarin, L7AE and a… | x-ray diffraction | B, F | SAM | 9 (best 0.74) |
| 3ID6 | Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex | x-ray diffraction | C | SAM | 2 (best 0.45) |
| 3ID6 | Crystal structure of sulfolobus solfataricus NOP5 (1-262) and fibrillarin complex | x-ray diffraction | C | SAM | 2 (best 0.45) |
| 3PLA | Crystal structure of a catalytically active substrate-bound box C/D RNP from Sulfolobus solfataricus | x-ray diffraction | E, F, M | SAH | 14 (best 0.85) |
| 3PLA | Crystal structure of a catalytically active substrate-bound box C/D rnp from sulfolobus solfataricus | x-ray diffraction | E, F, M | SAH | 14 (best 0.85) |
| P58032 | AlphaFold monomer V2.0 prediction for fibrillarin-like RRNA/TRNA 2'-O-methyltransferase (P58032) | predicted | A | — | 1 (best 0.44) |
Ligands
Experiment against prediction
- 3PLA chain F against the predicted model P58032: TM-score 0.99, RMSD 0.47 Å
- 3PLA chain F against the predicted model P58032: TM-score 0.99, RMSD 0.47 Å
- 3PLA chain E against the predicted model P58032: TM-score 0.99, RMSD 0.47 Å
- 3PLA chain E against the predicted model P58032: TM-score 0.99, RMSD 0.47 Å
- 3PLA chain M against the predicted model P58032: TM-score 0.99, RMSD 0.47 Å
- 3PLA chain M against the predicted model P58032: TM-score 0.99, RMSD 0.47 Å
- 3ID6 chain C against the predicted model P58032: TM-score 0.96, RMSD 1.00 Å
- 3ID6 chain C against the predicted model P58032: TM-score 0.96, RMSD 1.00 Å
- 3ID5 chain F against the predicted model P58032: TM-score 0.95, RMSD 1.49 Å
- 3ID5 chain F against the predicted model P58032: TM-score 0.95, RMSD 1.49 Å
Elsewhere
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