UniProt P56556

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (P56556)

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (UniProt P56556): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against…

UniProt: P56556
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
Experimental structures: 5
Predicted models: 1
Ligands: 1
Pockets: 10 · 4 records with a druggable one

Structures

6 records of P56556 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5XTB	Cryo-EM structure of human respiratory complex I matrix arm	electron microscopy	E	8Q1	3 (best 0.89)
5XTB	Cryo-EM structure of human respiratory complex I matrix arm	electron microscopy	E	8Q1	—
5XTD	Cryo-EM structure of human respiratory complex I	electron microscopy	E	8Q1	—
5XTH	Cryo-EM structure of human respiratory supercomplex I1III2IV1	electron microscopy	E	8Q1	3 (best 0.89)
5XTI	Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2	electron microscopy	E, BE	8Q1	3 (best 0.89)
P56556	AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6…	predicted	A	—	1 (best 0.72)

Ligands

8Q1 · S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy) butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate · in 5 records

Experiment against prediction

5XTI chain BE against the predicted model P56556: TM-score 0.97, RMSD 0.72 Å
5XTH chain E against the predicted model P56556: TM-score 0.97, RMSD 0.72 Å
5XTD chain E against the predicted model P56556: TM-score 0.97, RMSD 0.72 Å
5XTI chain E against the predicted model P56556: TM-score 0.97, RMSD 0.72 Å
5XTB chain E against the predicted model P56556: TM-score 0.97, RMSD 0.72 Å
5XTB chain E against the predicted model P56556: TM-score 0.97, RMSD 0.72 Å

Elsewhere

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