UniProt P56288
Probable translation initiation factor eIF-2B subunit gamma (P56288)
Probable translation initiation factor eIF-2B subunit gamma (UniProt P56288): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P56288
- Protein
- Probable translation initiation factor eIF-2B subunit gamma
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
5 records of P56288 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5B04 | Crystal structure of the eukaryotic translation initiation factor 2B from schizosaccharomyces pombe | x-ray diffraction | E, F | — | — |
| 6JLY | eIF2a - eIF2B complex | x-ray diffraction | E, F | PO4 | 6 (best 0.75) |
| 6JLY | EIF2A - EIF2B complex | x-ray diffraction | E, F | PO4 | — |
| 6JLZ | P-EIF2A - EIF2B complex | x-ray diffraction | E, F | PO4 | — |
| P56288 | AlphaFold monomer V2.0 prediction for probable translation initiation factor eif-2B subunit gamma… | predicted | A | — | — |
Ligands
- PO4 · Phosphate ion · in 3 records
Experiment against prediction
- 5B04 chain F against the predicted model P56288: TM-score 0.98, RMSD 1.01 Å
- 6JLZ chain F against the predicted model P56288: TM-score 0.98, RMSD 1.12 Å
- 5B04 chain E against the predicted model P56288: TM-score 0.98, RMSD 1.11 Å
- 6JLY chain F against the predicted model P56288: TM-score 0.98, RMSD 1.16 Å
- 6JLY chain F against the predicted model P56288: TM-score 0.98, RMSD 1.16 Å
- 6JLZ chain E against the predicted model P56288: TM-score 0.98, RMSD 1.17 Å
- 6JLY chain E against the predicted model P56288: TM-score 0.98, RMSD 1.24 Å
- 6JLY chain E against the predicted model P56288: TM-score 0.98, RMSD 1.24 Å
Elsewhere
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