UniProt P56282
DNA polymerase epsilon subunit 2 (P56282)
DNA polymerase epsilon subunit 2 (UniProt P56282): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P56282
- Protein
- DNA polymerase epsilon subunit 2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
5 records of P56282 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2V6Z | Solution Structure of Amino-Terminal Domain of Human DNA Polymerase Epsilon Subunit B | solution nmr | M | — | — |
| 2V6Z | Solution structure of amino-terminal domain of human DNA polymerase epsilon subunit B | solution nmr | M | — | — |
| 5VBN | Crystal structure of human DNA polymerase epsilon B-subunit in complex with C-terminal domain of… | x-ray diffraction | A, E | SO4 | — |
| 7PLO | H. sapiens replisome-CUL2/LRR1 complex | electron microscopy | A | SO4 | 1 (best 0.78) |
| P56282 | AlphaFold monomer V2.0 prediction for DNA polymerase epsilon subunit 2 (P56282) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 5VBN chain A against the predicted model P56282: TM-score 0.99, RMSD 0.84 Å
- 5VBN chain E against the predicted model P56282: TM-score 0.99, RMSD 0.84 Å
- 2V6Z chain M against the predicted model P56282: TM-score 0.92, RMSD 0.97 Å
- 2V6Z chain M against the predicted model P56282: TM-score 0.92, RMSD 0.97 Å
- 7PLO chain A against the predicted model P56282: TM-score 0.84, RMSD 3.01 Å
Elsewhere
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