UniProt P56273
P56273
P56273 (UniProt P56273): 24 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P56273
- Experimental structures
- 24
- Predicted models
- 1
Structures
25 records of P56273 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1TTV | NMR Structure of a Complex Between MDM2 and a Small Molecule Inhibitor | solution nmr | A | — | — |
| 1TTV | NMR structure of a complex between MDM2 and a small molecule inhibitor | solution nmr | A | — | — |
| 1YCQ | Xenopus laevis MDM2 bound to the transactivation domain of human P53 | x-ray diffraction | A | — | — |
| 1YCQ | Xenopus laevis MDM2 bound to the transactivation domain of human P53 | x-ray diffraction | A | — | — |
| 4IPF | The 1.7A crystal structure of humanized Xenopus MDM2 with RO5045337 | x-ray diffraction | A | — | — |
| 4IPF | The 1.7A crystal structure of humanized xenopus MDM2 with RO5045337 | x-ray diffraction | A | — | — |
| 4J3E | The 1.9A crystal structure of humanized Xenopus Mdm2 with nutlin-3a | x-ray diffraction | A | — | — |
| 4J3E | The 1.9A crystal structure of humanized xenopus MDM2 with nutlin-3A | x-ray diffraction | A | — | — |
| 4J74 | The 1.2A crystal structure of humanized Xenopus MDM2 with RO0503918 - a nutlin fragment | x-ray diffraction | A | — | — |
| 4J74 | The 1.2A crystal structure of humanized xenopus MDM2 with RO0503918 - a nutlin fragment | x-ray diffraction | A | — | — |
| 4J7D | The 1.25A crystal structure of humanized Xenopus MDM2 with a nutlin fragment, RO5045331 | x-ray diffraction | A | — | — |
| 4J7D | The 1.25A crystal structure of humanized xenopus MDM2 with a nutlin fragment, RO5045331 | x-ray diffraction | A | — | — |
| 4J7E | The 1.63A crystal structure of humanized Xenopus MDM2 with a nutlin fragment, RO5524529 | x-ray diffraction | A | — | — |
| 4J7E | The 1.63A crystal structure of humanized xenopus MDM2 with a nutlin fragment, RO5524529 | x-ray diffraction | A | — | — |
| 4JRG | The 1.9A crystal structure of humanized Xenopus MDM2 with RO5313109 - a pyrrolidine MDM2 inhibitor | x-ray diffraction | A, B | — | — |
| 4JRG | The 1.9A crystal structure of humanized xenopus MDM2 with RO5313109 - a pyrrolidine MDM2 inhibitor | x-ray diffraction | A, B | — | — |
| 4JSC | The 2.5A crystal structure of humanized Xenopus MDM2 with RO5316533 - a pyrrolidine MDM2 inhibitor | x-ray diffraction | A, B | — | — |
| 4JSC | The 2.5A crystal structure of humanized xenopus MDM2 with RO5316533 - a pyrrolidine MDM2 inhibitor | x-ray diffraction | A, B | — | — |
| 4LWT | The 1.6A Crystal Structure of Humanized Xenopus MDM2 with RO5027344 | x-ray diffraction | A | — | — |
| 4LWT | The 1.6A crystal structure of humanized xenopus MDM2 with RO5027344 | x-ray diffraction | A | — | — |
| 4LWU | The 1.14A Crystal Structure of Humanized Xenopus MDM2 with RO5499252 | x-ray diffraction | A | — | — |
| 4LWU | The 1.14A crystal structure of humanized xenopus MDM2 with RO5499252 | x-ray diffraction | A | — | — |
| 4LWV | The 2.3A Crystal Structure of Humanized Xenopus MDM2 with RO5545353 | x-ray diffraction | A, B, C | — | — |
| 4LWV | The 2.3A crystal structure of humanized xenopus MDM2 with RO5545353 | x-ray diffraction | A, B, C | — | — |
| P56273 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase MDM2 (P56273) | predicted | A | — | — |
Experiment against prediction
- 4JRG chain A against the predicted model P56273: TM-score 0.97, RMSD 0.60 Å
- 4JRG chain A against the predicted model P56273: TM-score 0.97, RMSD 0.60 Å
- 4LWT chain A against the predicted model P56273: TM-score 0.96, RMSD 0.77 Å
- 4LWT chain A against the predicted model P56273: TM-score 0.96, RMSD 0.77 Å
- 4J7D chain A against the predicted model P56273: TM-score 0.96, RMSD 0.80 Å
- 4J7D chain A against the predicted model P56273: TM-score 0.96, RMSD 0.80 Å
- 1YCQ chain A against the predicted model P56273: TM-score 0.96, RMSD 0.75 Å
- 1YCQ chain A against the predicted model P56273: TM-score 0.96, RMSD 0.75 Å
- 4J7E chain A against the predicted model P56273: TM-score 0.96, RMSD 0.84 Å
- 4J7E chain A against the predicted model P56273: TM-score 0.96, RMSD 0.84 Å
Elsewhere
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