UniProt P56255
ATP-dependent DNA helicase PcrA (P56255)
ATP-dependent DNA helicase PcrA (UniProt P56255), EC 3.6.4.12: 12 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P56255
- Protein
- ATP-dependent DNA helicase PcrA
- EC
- 3.6.4.12
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
13 records of P56255 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PJR | Structure of DNA helicase | x-ray diffraction | A | — | — |
| 1PJR | Structure of DNA helicase | x-ray diffraction | A | — | — |
| 1QHG | Structure of DNA helicase mutant with adpnp | x-ray diffraction | A | — | — |
| 1QHG | Structure of DNA helicase mutant with adpnp | x-ray diffraction | A | — | — |
| 1QHH | Structure of DNA helicase with adpnp | x-ray diffraction | A, B, C, D | — | — |
| 1QHH | Structure of DNA helicase with adpnp | x-ray diffraction | A, B, C, D | — | — |
| 2PJR | Helicase product complex | x-ray diffraction | A, B, F, G | — | — |
| 2PJR | Helicase product complex | x-ray diffraction | A, B, F, G | — | — |
| 3PJR | Helicase substrate complex | x-ray diffraction | A | — | — |
| 3PJR | Helicase substrate complex | x-ray diffraction | A | — | — |
| 5DMA | Crystal structure of C-terminal tudor domain in PcrA/UvrD helicase | x-ray diffraction | A | — | — |
| 5DMA | Crystal structure of C-terminal tudor domain in PCRA/UVRD helicase | x-ray diffraction | A | — | — |
| P56255 | AlphaFold monomer V2.0 prediction for ATP-dependent DNA helicase pcra (P56255) | predicted | A | — | 7 (best 0.81) |
Experiment against prediction
- 1QHH chain D against the predicted model P56255: TM-score 0.98, RMSD 0.54 Å
- 1QHH chain D against the predicted model P56255: TM-score 0.98, RMSD 0.54 Å
- 2PJR chain A against the predicted model P56255: TM-score 0.98, RMSD 1.33 Å
- 2PJR chain A against the predicted model P56255: TM-score 0.98, RMSD 1.33 Å
- 2PJR chain B against the predicted model P56255: TM-score 0.98, RMSD 0.64 Å
- 2PJR chain B against the predicted model P56255: TM-score 0.98, RMSD 0.64 Å
- 1QHH chain C against the predicted model P56255: TM-score 0.97, RMSD 0.66 Å
- 1QHH chain C against the predicted model P56255: TM-score 0.97, RMSD 0.66 Å
- 2PJR chain F against the predicted model P56255: TM-score 0.97, RMSD 1.56 Å
- 2PJR chain F against the predicted model P56255: TM-score 0.97, RMSD 1.56 Å
Elsewhere
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