UniProt P55917
Gap junction alpha-8 protein (P55917)
Gap junction alpha-8 protein (UniProt P55917): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P55917
- Protein
- Gap junction alpha-8 protein
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
9 records of P55917 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6MHY | Structure of connexin-50 intercellular gap junction channel at 3.4 angstrom resolution by cryoEM | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 6MHY | Structure of connexin-50 intercellular gap junction channel at 3.4 ångström resolution by cryoem | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 7JJP | Sheep connexin-50 at 1.9 ångströms resolution by cryoem | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | MC3 | — |
| 7JLW | Sheep Connexin-50 at 2.5 angstroms resolution, Lipid Class 1 | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | MC3 | 20 (best 0.63) |
| 7JLW | Sheep connexin-50 at 2.5 ångströms resolution, lipid class 1 | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | MC3 | — |
| 7JM9 | Sheep Connexin-50 at 2.5 angstroms reoslution, Lipid Class 2 | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | MC3 | — |
| 7JM9 | Sheep connexin-50 at 2.5 ångströms reoslution, lipid class 2 | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | MC3 | — |
| 7JMC | Sheep connexin-50 at 2.5 ångströms resolution, lipid class 3 | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | MC3 | — |
| P55917 | AlphaFold monomer V2.0 prediction for gap junction alpha-8 protein (P55917) | predicted | A | — | — |
Ligands
- MC3 · 1,2-dimyristoyl-rac-glycero-3-phosphocholine · in 6 records
Experiment against prediction
- 6MHY chain L against the predicted model P55917: TM-score 0.93, RMSD 1.52 Å
- 6MHY chain L against the predicted model P55917: TM-score 0.93, RMSD 1.52 Å
- 6MHY chain E against the predicted model P55917: TM-score 0.93, RMSD 1.52 Å
- 6MHY chain E against the predicted model P55917: TM-score 0.93, RMSD 1.52 Å
- 6MHY chain A against the predicted model P55917: TM-score 0.93, RMSD 1.52 Å
- 6MHY chain A against the predicted model P55917: TM-score 0.93, RMSD 1.52 Å
- 6MHY chain G against the predicted model P55917: TM-score 0.93, RMSD 1.52 Å
- 6MHY chain G against the predicted model P55917: TM-score 0.93, RMSD 1.52 Å
- 6MHY chain D against the predicted model P55917: TM-score 0.93, RMSD 1.52 Å
- 6MHY chain D against the predicted model P55917: TM-score 0.93, RMSD 1.52 Å
Elsewhere
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