UniProt P55197
Protein AF-10 (P55197)
Protein AF-10 (UniProt P55197): 9 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P55197
- Protein
- Protein AF-10
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 1 · 0 records with a druggable one
Structures
10 records of P55197 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5DAG | Crystal structure of pzp domain of human AF10 protein | x-ray diffraction | A | — | — |
| 5DAH | Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide | x-ray diffraction | A, B | ZN, SO4 | — |
| 5DAH | Crystal structure of pzp domain of human AF10 protein fused with histone H3 peptide | x-ray diffraction | A, B | — | — |
| 6CKN | Crystal structure of an AF10 fragment | x-ray diffraction | A, B | UNX | — |
| 6CKO | Crystal structure of an AF10 fragment | x-ray diffraction | A, B | ZN, UNX | 1 (best 0.37) |
| 6CKO | Crystal structure of an AF10 fragment | x-ray diffraction | A, B | ZN, UNX | — |
| 6JN2 | Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10 | x-ray diffraction | A | — | — |
| 6JN2 | Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10 | x-ray diffraction | A | — | — |
| 7MJU | Crystal structure of human AF10 pzp bound to histone H3 tail | x-ray diffraction | A | ZN | — |
| P55197 | AlphaFold monomer V2.0 prediction for protein af-10 (P55197) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5DAG chain A against the predicted model P55197: TM-score 0.98, RMSD 0.72 Å
- 5DAH chain A against the predicted model P55197: TM-score 0.98, RMSD 0.88 Å
- 5DAH chain A against the predicted model P55197: TM-score 0.98, RMSD 0.88 Å
- 5DAH chain B against the predicted model P55197: TM-score 0.96, RMSD 1.37 Å
- 5DAH chain B against the predicted model P55197: TM-score 0.96, RMSD 1.37 Å
- 7MJU chain A against the predicted model P55197: TM-score 0.92, RMSD 1.10 Å
- 6CKN chain A against the predicted model P55197: TM-score 0.71, RMSD 2.09 Å
- 6CKN chain B against the predicted model P55197: TM-score 0.70, RMSD 2.11 Å
- 6CKO chain B against the predicted model P55197: TM-score 0.61, RMSD 2.94 Å
- 6CKO chain B against the predicted model P55197: TM-score 0.61, RMSD 2.94 Å
Elsewhere
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