UniProt P55087
Aquaporin-4 (P55087)
Aquaporin-4 (UniProt P55087): 5 experimental structures and 1 predicted model on GenesisL1, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P55087
- Protein
- Aquaporin-4
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 36 · 3 records with a druggable one
Structures
6 records of P55087 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3GD8 | Crystal Structure of Human Aquaporin 4 at 1.8 and its Mechanism of Conductance | x-ray diffraction | A | — | — |
| 3GD8 | Crystal structure of human aquaporin 4 at 1.8 and its mechanism of conductance | x-ray diffraction | A | — | — |
| 8V8S | Structure of human AQP4 in lipid nanodisc | electron microscopy | A, B, C, D | — | 9 (best 0.80) |
| 8V91 | Structure of human AQP4 with a pathogenic autoantibody- rAB 58 | electron microscopy | A, B, C, D | — | 13 (best 0.82) |
| 8V9D | Structure of human AQP4 with a pathogenic autoantibody - rAB 186 | electron microscopy | A, B, C, D | — | 14 (best 0.80) |
| P55087 | AlphaFold monomer V2.0 prediction for aquaporin-4 (P55087) | predicted | A | — | — |
Experiment against prediction
- 8V8S chain A against the predicted model P55087: TM-score 1.00, RMSD 0.37 Å
- 8V8S chain C against the predicted model P55087: TM-score 1.00, RMSD 0.37 Å
- 8V8S chain B against the predicted model P55087: TM-score 1.00, RMSD 0.37 Å
- 8V8S chain D against the predicted model P55087: TM-score 1.00, RMSD 0.37 Å
- 3GD8 chain A against the predicted model P55087: TM-score 1.00, RMSD 0.39 Å
- 3GD8 chain A against the predicted model P55087: TM-score 1.00, RMSD 0.39 Å
- 8V91 chain A against the predicted model P55087: TM-score 0.99, RMSD 0.42 Å
- 8V91 chain C against the predicted model P55087: TM-score 0.99, RMSD 0.42 Å
- 8V91 chain D against the predicted model P55087: TM-score 0.99, RMSD 0.43 Å
- 8V91 chain B against the predicted model P55087: TM-score 0.99, RMSD 0.44 Å
Elsewhere
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