UniProt P54791
Origin recognition complex subunit 4 (P54791)
Origin recognition complex subunit 4 (UniProt P54791): 14 experimental structures on GenesisL1, 3 ligands bound, 49 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P54791
- Protein
- Origin recognition complex subunit 4
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 49 · 7 records with a druggable one
Structures
14 records of P54791 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5V8F | Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1 | electron microscopy | D | AGS | 8 (best 0.86) |
| 5V8F | Structural basis of MCM2-7 replicative helicase loading by orc-CDC6 and CDT1 | electron microscopy | D | AGS | — |
| 5ZR1 | Saccharomyces cerevisiae origin recognition complex bound to a 72-bp origin DNA containing acs and… | electron microscopy | D | AGS, MG | — |
| 6RQC | Cryo-EM structure of an MCM loading intermediate | electron microscopy | D | ATP, MG | 5 (best 0.89) |
| 6WGC | Atomic model of semi-attached mutant occm-DNA complex (orc-CDC6-CDT1- MCM2-7 with MCM6 whd… | electron microscopy | D | AGS | — |
| 6WGG | Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) | electron microscopy | D | AGS | 5 (best 0.88) |
| 6WGG | Atomic model of pre-insertion mutant occm-DNA COMPLEX(ORC-CDC6-CDT1- MCM2-7 with MCM6 whd… | electron microscopy | D | AGS | — |
| 6WGI | Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at… | electron microscopy | D | AGS | 5 (best 0.88) |
| 6WGI | Atomic model of the mutant occm (orc-CDC6-CDT1-MCM2-7 with MCM6 whd truncation) loaded on DNA at… | electron microscopy | D | AGS | — |
| 7MCA | Structure of the S. cerevisiae origin recognition complex bound to the replication initiator Cdc6… | electron microscopy | D | MG, AGS | 9 (best 0.88) |
| 7MCA | Structure of the S. cerevisiae origin recognition complex bound to the replication initiator CDC6… | electron microscopy | D | MG, AGS | — |
| 7TJF | S. cerevisiae ORC bound to 84 bp ARS1 DNA | electron microscopy | D | ATP, MG | 11 (best 0.88) |
| 9BCX | Cryo-EM structure of the S. cerevisiae ORC-Cdc6-Mcm2-7-DNA complex with a fully closed Mcm2-Mcm5… | electron microscopy | E | ATP, MG | 6 (best 0.88) |
| P54791 | AlphaFold monomer V2.0 prediction for origin recognition complex subunit 4 (P54791) | — | — | — |
Ligands
Elsewhere
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