UniProt P54278
Mismatch repair endonuclease PMS2 (P54278)
Mismatch repair endonuclease PMS2 (UniProt P54278), EC 3.1.-.-: 16 experimental structures on GenesisL1, 2 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P54278
- Protein
- Mismatch repair endonuclease PMS2
- EC
- 3.1.-.-
- Experimental structures
- 16
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 21 · 3 records with a druggable one
Structures
16 records of P54278 in the MolNFT archive: 16 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EA6 | N-terminal 40kDa fragment of NhPMS2 complexed with ADP | x-ray diffraction | A, B | — | — |
| 1EA6 | N-terminal 40KDA fragment of NHPMS2 complexed with ADP | x-ray diffraction | A, B | — | — |
| 1H7S | N-terminal 40kDa fragment of human PMS2 | x-ray diffraction | A, B | — | — |
| 1H7S | N-terminal 40KDA fragment of human PMS2 | x-ray diffraction | A, B | — | — |
| 1H7U | hPMS2-ATPgS | x-ray diffraction | A, B | — | — |
| 1H7U | HPMS2-ATPGS | x-ray diffraction | A, B | — | — |
| 5U5R | Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus… | x-ray diffraction | B | — | 1 (best 0.29) |
| 5U5R | Crystal structure and X-ray diffraction data collection of importin- alpha from mus musculus… | x-ray diffraction | B | — | — |
| 6MFQ | Crystal structure of a PMS2 variant | x-ray diffraction | A, B | — | — |
| 7RCB | Crystal Structure of a PMS2 VUS | x-ray diffraction | A, B | — | 7 (best 0.71) |
| 7RCB | Crystal structure of a PMS2 vus | x-ray diffraction | A, B | — | — |
| 7RCI | Crystal Structure of a PMS2 VUS with Substrate | x-ray diffraction | A, B | ATP, MG | 6 (best 0.69) |
| 7RCI | Crystal structure of a PMS2 vus with substrate | x-ray diffraction | A, B | ATP, MG | — |
| 7RCK | Crystal Structure of PMS2 with Substrate | x-ray diffraction | A, B | ATP, MG | 7 (best 0.74) |
| 7RCK | Crystal structure of PMS2 with substrate | x-ray diffraction | A, B | ATP, MG | — |
| P54278 | AlphaFold monomer V2.0 prediction for mismatch repair endonuclease PMS2 (P54278) | — | — | — |
Ligands
Elsewhere
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