UniProt P54071
Isocitrate dehydrogenase [NADP], mitochondrial (P54071)
Isocitrate dehydrogenase [NADP], mitochondrial (UniProt P54071), EC 1.1.1.42: 5 experimental structures on GenesisL1, 2 ligands bound, 17 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P54071
- Protein
- Isocitrate dehydrogenase [NADP], mitochondrial
- EC
- 1.1.1.42
- Experimental structures
- 5
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 17 · 2 records with a druggable one
Structures
5 records of P54071 in the MolNFT archive: 5 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5H3E | Crystal structure of mouse isocitrate dehydrogenases 2 K256Q mutant complexed with isocitrate | x-ray diffraction | A, B | MG, ICT | 8 (best 0.79) |
| 5H3E | Crystal structure of mouse isocitrate dehydrogenases 2 K256Q mutant complexed with isocitrate | x-ray diffraction | A, B | — | — |
| 5H3F | Crystal structure of mouse isocitrate dehydrogenases 2 complexed with isocitrate | x-ray diffraction | A, B | ICT, MG | 9 (best 0.75) |
| 5H3F | Crystal structure of mouse isocitrate dehydrogenases 2 complexed with isocitrate | x-ray diffraction | A, B | — | — |
| P54071 | AlphaFold monomer V2.0 prediction for isocitrate dehydrogenase [NADP], mitochondrial (P54071) | — | — | — |
Ligands
Elsewhere
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