UniProt P53762
Aryl hydrocarbon receptor nuclear translocator (P53762)
Aryl hydrocarbon receptor nuclear translocator (UniProt P53762): 26 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 38 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P53762
- Protein
- Aryl hydrocarbon receptor nuclear translocator
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 38 · 6 records with a druggable one
Structures
27 records of P53762 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4ZP4 | Crystal structure of the heterodimeric hif-2A:ARNT complex | x-ray diffraction | A, C | — | — |
| 4ZPH | Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with Proflavine | x-ray diffraction | A, C | — | — |
| 4ZPH | Crystal structure of the heterodimeric hif-2A:ARNT complex with proflavine | x-ray diffraction | A, C | — | — |
| 4ZPK | Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with HRE DNA | x-ray diffraction | A | — | — |
| 4ZPK | Crystal structure of the heterodimeric hif-2A:ARNT complex with hre DNA | x-ray diffraction | A | — | — |
| 4ZPR | Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA | x-ray diffraction | A | — | — |
| 4ZPR | Crystal structure of the heterodimeric hif-1A:ARNT complex with hre DNA | x-ray diffraction | A | — | — |
| 4ZQD | Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with the Benzoxadiazole Antagonist 0X3 | x-ray diffraction | A, C | — | — |
| 4ZQD | Crystal structure of the heterodimeric hif-2A:ARNT complex with the benzoxadiazole antagonist 0X3 | x-ray diffraction | A, C | — | — |
| 5NJ8 | Structural basis for aryl hydrocarbon receptor mediated gene activation | x-ray diffraction | B, D | ER3 | — |
| 5SY5 | Crystal structure of the heterodimeric NPAS1-arnt complex | x-ray diffraction | A, C, E | — | — |
| 5SY7 | Crystal Structure of the Heterodimeric NPAS3-ARNT Complex with HRE DNA | x-ray diffraction | A | — | 7 (best 0.80) |
| 5SY7 | Crystal structure of the heterodimeric NPAS3-arnt complex with hre DNA | x-ray diffraction | A | — | — |
| 6E3S | Crystal structure of the heterodimeric hif-2 complex with antagonist PT2385 | x-ray diffraction | A | — | — |
| 6E3T | Crystal Structure of the Heterodimeric HIF-2 Complex with Antagonist T1001 | x-ray diffraction | A | — | 4 (best 0.66) |
| 6E3T | Crystal structure of the heterodimeric hif-2 complex with antagonist T1001 | x-ray diffraction | A | — | — |
| 6E3U | Crystal Structure of the Heterodimeric HIF-2 Complex with Agonist M1001 | x-ray diffraction | A | — | 7 (best 0.71) |
| 6E3U | Crystal structure of the heterodimeric hif-2 complex with agonist M1001 | x-ray diffraction | A | — | — |
| 7V7L | Crystal Structure of the Heterodimeric HIF-3a:ARNT Complex | x-ray diffraction | A | — | 9 (best 0.67) |
| 7V7L | Crystal structure of the heterodimeric hif-3A:ARNT complex | x-ray diffraction | A | — | — |
| 7V7W | Crystal structure of the heterodimeric hif-3A:ARNT complex with oleoylethanolamide (oea) | x-ray diffraction | A | — | — |
| 7VNI | AHR-ARNT PAS-B heterodimer | x-ray diffraction | D, C | SO4 | 1 (best 0.31) |
| 7VNI | Ahr-arnt pas-B heterodimer | x-ray diffraction | D, C | SO4 | — |
| 7W80 | Crystal Structure of the Heterodimeric HIF-2 in Complex with Antagonist Belzutifan | x-ray diffraction | A | — | 5 (best 0.75) |
| 7XHV | Crystal Structure of the NPAS4-ARNT heterodimer in complex with DNA | x-ray diffraction | A | — | 5 (best 0.84) |
| 7XI4 | Crystal Structure of the NPAS4-ARNT heterodimer in complex with DNA | x-ray diffraction | A | — | — |
| P53762 | AlphaFold monomer V2.0 prediction for aryl hydrocarbon receptor nuclear translocator (P53762) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7VNI chain C against the predicted model P53762: TM-score 0.99, RMSD 0.41 Å
- 7VNI chain C against the predicted model P53762: TM-score 0.99, RMSD 0.41 Å
- 7VNI chain D against the predicted model P53762: TM-score 0.99, RMSD 0.42 Å
- 7VNI chain D against the predicted model P53762: TM-score 0.99, RMSD 0.42 Å
- 5SY5 chain A against the predicted model P53762: TM-score 0.89, RMSD 2.49 Å
- 5SY5 chain C against the predicted model P53762: TM-score 0.88, RMSD 2.88 Å
- 5SY5 chain E against the predicted model P53762: TM-score 0.87, RMSD 3.07 Å
- 6E3S chain A against the predicted model P53762: TM-score 0.87, RMSD 2.44 Å
- 7W80 chain A against the predicted model P53762: TM-score 0.86, RMSD 2.53 Å
- 6E3U chain A against the predicted model P53762: TM-score 0.86, RMSD 2.65 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.