UniProt P53621
Coatomer subunit alpha (P53621)
Coatomer subunit alpha (UniProt P53621): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P53621
- Protein
- Coatomer subunit alpha
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 21 · 3 records with a druggable one
Structures
7 records of P53621 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6PBG | Crystal structure of WD-repeat domain of human coatomer subunit Alpha (COPA) | x-ray diffraction | A | UNX | 1 (best 0.79) |
| 6PBG | Crystal structure of wd-repeat domain of human coatomer subunit alpha (copa) | x-ray diffraction | A | UNX | — |
| 6TZT | Crystal structure of human alpha/epsilon-COP of the COPI vesicular coat bound to alpha-COP STM2 | x-ray diffraction | B, D | — | 8 (best 0.78) |
| 6TZT | Crystal structure of human ALPHA/EPSILON-cop of the copi vesicular coat bound to alpha-cop STM2 | x-ray diffraction | B, D | — | — |
| 6U3V | Crystal structure of human alpha/epsilon-COP of the COPI vesicular coat bound to alpha-COP STM1 | x-ray diffraction | B, D | — | 12 (best 0.78) |
| 6U3V | Crystal structure of human ALPHA/EPSILON-cop of the copi vesicular coat bound to alpha-cop STM1 | x-ray diffraction | B, D | — | — |
| P53621 | AlphaFold monomer V2.0 prediction for coatomer subunit alpha (P53621) | predicted | A | — | — |
Ligands
- UNX · Unknown atom or ion · in 2 records
Experiment against prediction
- 6PBG chain A against the predicted model P53621: TM-score 0.98, RMSD 0.87 Å
- 6PBG chain A against the predicted model P53621: TM-score 0.98, RMSD 0.87 Å
- 6U3V chain D against the predicted model P53621: TM-score 0.97, RMSD 1.54 Å
- 6U3V chain D against the predicted model P53621: TM-score 0.97, RMSD 1.54 Å
- 6TZT chain D against the predicted model P53621: TM-score 0.97, RMSD 1.57 Å
- 6TZT chain D against the predicted model P53621: TM-score 0.97, RMSD 1.57 Å
- 6TZT chain B against the predicted model P53621: TM-score 0.95, RMSD 1.61 Å
- 6TZT chain B against the predicted model P53621: TM-score 0.95, RMSD 1.61 Å
- 6U3V chain B against the predicted model P53621: TM-score 0.94, RMSD 1.70 Å
- 6U3V chain B against the predicted model P53621: TM-score 0.94, RMSD 1.70 Å
Elsewhere
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