UniProt P53370

Nucleoside diphosphate-linked moiety X motif 6 (P53370)

Nucleoside diphosphate-linked moiety X motif 6 (UniProt P53370): 4 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P53370
Protein: Nucleoside diphosphate-linked moiety X motif 6
Experimental structures: 4
Predicted models: 1
Pockets: 2 · 1 record with a druggable one

Structures

5 records of P53370 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
3FXT	Crystal structure of the N-terminal domain of human NUDT6	x-ray diffraction	A, B, C, D, E, F, G, H	—	—
3FXT	Crystal structure of the N-terminal domain of human NUDT6	x-ray diffraction	A, B, C, D, E, F, G, H	—	—
3H95	Crystal structure of the NUDIX domain of NUDT6	x-ray diffraction	A	—	—
3H95	Crystal structure of the nudix domain of NUDT6	x-ray diffraction	A	—	—
P53370	AlphaFold monomer V2.0 prediction for nucleoside diphosphate-linked moiety X motif 6 (P53370)	predicted	A	—	2 (best 0.63)

Experiment against prediction

3FXT chain D against the predicted model P53370: TM-score 0.93, RMSD 1.26 Å
3FXT chain D against the predicted model P53370: TM-score 0.93, RMSD 1.26 Å
3FXT chain E against the predicted model P53370: TM-score 0.93, RMSD 1.37 Å
3FXT chain E against the predicted model P53370: TM-score 0.93, RMSD 1.37 Å
3H95 chain A against the predicted model P53370: TM-score 0.93, RMSD 1.61 Å
3H95 chain A against the predicted model P53370: TM-score 0.93, RMSD 1.61 Å
3FXT chain A against the predicted model P53370: TM-score 0.92, RMSD 1.45 Å
3FXT chain A against the predicted model P53370: TM-score 0.92, RMSD 1.45 Å
3FXT chain H against the predicted model P53370: TM-score 0.92, RMSD 1.31 Å
3FXT chain H against the predicted model P53370: TM-score 0.92, RMSD 1.31 Å

Elsewhere

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