UniProt P53298
Inner kinetochore subunit OKP1 (P53298)
Inner kinetochore subunit OKP1 (UniProt P53298): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 42 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P53298
- Protein
- Inner kinetochore subunit OKP1
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 42 · 6 records with a druggable one
Structures
13 records of P53298 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NUW | Yeast CTF19 complex | electron microscopy | F | — | — |
| 6QLD | Structure of inner kinetochore CCAN-Cenp-A complex | electron microscopy | Q | — | — |
| 6QLD | Structure of inner kinetochore ccan-cenp-a complex | electron microscopy | Q | — | — |
| 6QLE | Structure of inner kinetochore CCAN complex | electron microscopy | Q | — | 5 (best 0.83) |
| 6QLE | Structure of inner kinetochore ccan complex | electron microscopy | Q | — | — |
| 6QLF | Structure of inner kinetochore CCAN complex with mask1 | electron microscopy | Q | — | 9 (best 0.83) |
| 6QLF | Structure of inner kinetochore ccan complex with MASK1 | electron microscopy | Q | — | — |
| 8OVW | Cryo-EM structure of CBF1-CCAN bound topologically to centromeric DNA | electron microscopy | Q | — | 8 (best 0.80) |
| 8OVX | Cryo-EM structure of yeast CENP-OPQU+ bound to the CENP-A N-terminus | electron microscopy | Q | — | 7 (best 0.74) |
| 8OW0 | Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome | electron microscopy | Q | — | 5 (best 0.87) |
| 8OW1 | Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | electron microscopy | Q, QQ | — | 8 (best 0.85) |
| 8T0P | Structure of Cse4 bound to Ame1 and Okp1 | x-ray diffraction | A | SO4 | — |
| P53298 | AlphaFold monomer V2.0 prediction for inner kinetochore subunit OKP1 (P53298) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 8OVX chain Q against the predicted model P53298: TM-score 0.75, RMSD 2.18 Å
- 6QLF chain Q against the predicted model P53298: TM-score 0.69, RMSD 2.88 Å
- 6QLF chain Q against the predicted model P53298: TM-score 0.69, RMSD 2.88 Å
- 6QLD chain Q against the predicted model P53298: TM-score 0.69, RMSD 2.98 Å
- 6QLD chain Q against the predicted model P53298: TM-score 0.69, RMSD 2.98 Å
- 8T0P chain A against the predicted model P53298: TM-score 0.68, RMSD 3.27 Å
- 8OW1 chain QQ against the predicted model P53298: TM-score 0.67, RMSD 4.00 Å
- 8OW1 chain Q against the predicted model P53298: TM-score 0.66, RMSD 3.58 Å
- 6QLE chain Q against the predicted model P53298: TM-score 0.66, RMSD 3.10 Å
- 6QLE chain Q against the predicted model P53298: TM-score 0.66, RMSD 3.10 Å
Elsewhere
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